Prevalence of Peste-des-petits-ruminant virus antibodies in cattle, buffaloes, sheep and goats in India
Prevalence of Peste-des-petits-ruminant virus antibodies in cattle, buffaloes, sheep and goats in India
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DOI：
10.1007/s13337-013-0177-5
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发表时间：
2014-01-01
影响因子：
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通讯作者：
Rahman, H.
中科院分区：
文献类型：
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作者：
Balamurugan, V.;Krishnamoorthy, P.;Rahman, H.
本研究描述了2011年期间使用从印度五个邦的不同村庄随机收集的血清样本在牛，水牛，绵羊和山羊中进行的小反刍兽疫病毒（PPRV）抗体的流行情况。从印度5个邦（安得拉邦、古吉拉特邦、查谟和克什米尔、马哈拉施特拉邦和拉贾斯坦邦）的52个地区共收集1，498份血清样本[ n = 605（牛）; n = 432（水牛）; n = 173（绵羊）; n = 288（山羊）]，并使用基于PPR单克隆抗体的竞争性ELISA试剂盒筛选PPRV特异性抗体。对1,498份样品的分析表明，总的血清阳性率为21.83%，其中牛为11.07%，水牛为16.20%，绵羊为45.66%，山羊为38.54%。本报告介绍了在牛、水牛、绵羊和山羊中疑似亚临床、不明显或非致死或恢复感染的情况下的PPRV特异性抗体的结果。PPRV抗体的存在表明牛暴露于PPRV感染，这意味着牛和水牛作为该病毒的亚临床宿主的重要性，除了该疾病在绵羊和山羊中的广泛存在之外。本研究还表明，在自然条件下，PPRV抗体在表面健康的家畜中流行，21.83%的家畜免于PPRV再感染。这反过来又有助于在该特定地理区域实施疾病控制战略，如疫苗接种。
The present study describes the prevalence of Peste-des-petits-ruminant virus (PPRV) antibodies in cattle, buffaloes, sheep and goats carried out during the period 2011 using the serum samples randomly collected from different villages of five states of India. A total of 1,498 serum samples [ n = 605 (cattle); n = 432 (buffaloes); n = 173 (sheep); n = 288 (goats)] were collected from 52 districts in five states (Andhra Pradesh, Gujarat, Jammu and Kashmir, Maharashtra and Rajasthan) of India and were screened for PPRV-specific antibodies by using PPR monoclonal antibody-based competitive ELISA kit. Analysis of 1,498 samples indicates that an overall seroprevalence of 21.83 % with 11.07 % in cattle, 16.20 % in buffaloes, 45.66 % in sheep and 38.54 % in goats. This report presents the results of PPRV-specific antibodies in situations where the subclinical, inapparent or nonlethal or recovery of infection was suspected in cattle, buffaloes, sheep and goats. The presence of PPRV antibodies demonstrate that bovines are exposed to PPRV infection and it implies the importance of cattle and buffaloes as subclinical hosts for the virus besides widespread presence of the disease in sheep and goats. Further, the study showed that the prevalence of PPRV antibodies in apparently healthy livestock under natural situation, 21.83 % of the animals were protected from PPRV reinfection. This inturn help in the implementation of disease control strategies such as vaccination in that particular geographical area.