German guidelines for the diagnosis and therapy of localized scleroderma
German guidelines for the diagnosis and therapy of localized scleroderma
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DOI：
10.1111/ddg.12724
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发表时间：
2016-02-01
影响因子：
3.6
通讯作者：
Hunzelmann, Nicolas
中科院分区：
文献类型：
--
作者：
Kreuter, Alexander;Krieg, Thomas;Hunzelmann, Nicolas
局限性硬皮病是一组异质性的硬皮病皮肤疾病。根据亚型、严重程度和受累部位，可能累及邻近结构，如脂肪组织、肌肉、关节和骨骼。这是对现有德国AWMF（德国科学医学会协会）指南（分类：S2k）的更新。这些指南概述了局限性硬皮病的定义、流行病学、分类、发病机制、实验室检查、组织病理学、临床评分系统以及影像学和基于器械的检查。此外，基于共识的建议，根据其临床亚型的管理局限性硬皮病。治疗建议在治疗算法中提出。没有任何制药公司提供资金支持。该指南有效期至2019年7月。
Localized scleroderma designates a heterogeneous group of sclerotic skin disorders. Depending on the subtype, severity, and site affected, adjacent structures such as adipose tissue, muscles, joints, and bones may be involved. This is an update of the existing German AWMF (Association of the Scientific Medical Societies in Germany) guidelines (classification: S2k). These guidelines provide an overview of the definition, epidemiology, classification, pathogenesis, laboratory workup, histopathology, clinical scoring systems, as well as imaging and device-based workup of localized scleroderma. Moreover, consensus-based recommendations are given on the management of localized scleroderma depending on its clinical subtype. Treatment recommendations are presented in a therapeutic algorithm. No financial support was given by any pharmaceutical company. The guidelines are valid until July 2019.