Guided bone regeneration: integration of a resorbable membrane and a bone graft material.
Guided bone regeneration: integration of a resorbable membrane and a bone graft material.
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引导骨再生：可吸收膜和骨移植材料的整合。
DOI：
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发表时间：
1997
期刊：
影响因子：
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通讯作者：
S. Lynch
中科院分区：
文献类型：
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作者：
S. Kay;L. Wisner;M. Marxer;S. Lynch
引导骨再生主要依赖于四个原则——排除不需要的组织和细胞、空间的创造和维护、保护下面的血凝块以及伤口稳定。为了成功地发生骨再生，大的骨缺损需要底层的移植材料和细胞闭塞膜。本文的学习目标是回顾引导骨再生的历史和原理，并描述非常适合骨再生手术的缓慢吸收双层胶原膜的特征。讨论了骨传导性骨移植材料及其支撑上覆胶原膜并充当血管和骨形成细胞向内生长的基质的能力。
Guided bone regeneration relies primarily on four principles--exclusion of unwanted tissues and cells, space creation and maintenance, protection of the underlying blood clot, and wound stabilization. For successful bone regeneration to occur, large bony defects require an underlying grafting material and a cell-occlusive membrane. The learning objective of this article is to review the history and principles of guided bone regeneration and describe the characteristics of a slowly resorbing bilayer collagen membrane, well suited for bone regeneration procedures. An osteoconductive bone grafting material and its ability to support the overlying collagen membrane and serve as a matrix for the ingrowth of vascular and bone-forming cells are discussed.