Adenovirus Type 3 Outbreak in Connecticut Associated With a Novel Variant
Adenovirus Type 3 Outbreak in Connecticut Associated With a Novel Variant
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DOI：
10.1002/jmv.21539
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发表时间：
2009-08-01
影响因子：
12.7
通讯作者：
Gray, Gregory C.
中科院分区：
文献类型：
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作者：
Landry, Marie L.;Lebeck, Mark G.;Gray, Gregory C.
2006年至2007年，康涅狄格州纽黑文市爆发了一次腺病毒爆发。分子分型显示 3 型腺病毒感染增加了一倍。限制性内切酶分析 (REA) 表明 CT 爆发很大程度上是由于新型 Ad3a51 菌株的显着增加。此次疫情是美国首次检测到 Ad3a51。虽然大多数感染是轻微的，但 3 岁以下儿童患严重疾病的风险增加，一名患有基础疾病的患者死亡。 J. Med。病毒。 81:1380-1384, 2009。(C) 2009 Wiley-Liss, Inc.
An adenovirus outbreak occurred in New Haven, Connecticut in 2006-2007. Molecular typing revealed a twofold increase in adenovirus type 3 infections. Restriction enzyme analysis (REA) indicated that the CT outbreak was largely due to a marked increase in the novel Ad3a51 strain. This outbreak represents the first detection of Ad3a51 in the United States. While most infections were mild, children under 3 were at increased risk for severe disease and one patient with underlying disease died. J. Med. Virol. 81:1380-1384, 2009. (C) 2009 Wiley-Liss, Inc.