Effect of pregnancy on the auditory and visual reaction time
Effect of pregnancy on the auditory and visual reaction time
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怀孕对听觉和视觉反应时间的影响
DOI：
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发表时间：
2017
期刊：
影响因子：
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通讯作者：
A. Verma
中科院分区：
文献类型：
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作者：
Rupal I. Mehta;Naren Kurmi;M. Kaur;A. Verma
背景资料：听觉和视觉通路是复杂的多突触神经元回路，在各种神经激素调节剂的影响下易于改变电导率。女性性类固醇激素在月经周期和妊娠的不同阶段对这些回路有明显的影响。研究方法：本研究旨在了解不同孕期听觉和视觉反应时的变化。另取健康非孕妇女经前期作为对照组（NP组，n=30），根据妊娠时间长短将病例分为T1、T2、T3组，每组30例。结果：使用RTM-608（Medicaid）测量了我院妇产科的ART和VRT。记录观察结果并使用单因素ANOVA和事后Tukey检验进行分析。与未妊娠组相比，在T1组中观察到听觉和视觉通路的反应时间显著增加（p<0.001）。而T2和T3组与NP组相比，ART无显著差异，VRT无显著增加。反应时间的增加可能归因于妊娠早期HCG水平的升高，从而在此期间调节神经元传导性。结论：而T2组和T3组反应时无显著增加或相似，可能是由于雌激素和孕激素水平升高所致。因此，这些激素对神经元的兴奋性、可塑性和兴奋性具有神经调节作用，但HCG的直接作用有待进一步探讨。
Background: The auditory and visual pathways are complex multi-synaptic neuronal circuits prone to alteration in conductivity under the influence of various neuro-hormonal modulators. The female sex steroids have shown significant effect on these circuits during different phases on menstrual cycle and pregnancy. Methods: The present study was designed with an aim to find out the auditory and visual reaction time variations during different trimesters of pregnancy. The healthy non pregnant women, in premenstrual phase were grouped as controls (Group NP; n=30) whereas the cases were further divided into 3 groups depending on the duration of pregnancy as Groups T1,T2and T3 with 30 volunteers in each. Results: The ART and VRT were measured using RTM-608 (Medicaid) in the Obstetrics and Gynaecology department of our hospital. The observations were recorded and analysed using one way ANOVA and post hoc Tukey test. A significant increase (p<0.001) in reaction time of both the auditory and visual pathways has been observed in Group T1 as compared to Group non-pregnant. Whereas Group T2 and T3 had shown not much difference of ART and non-significant increase of VRT when compared to Group NP. The increased reaction time could be attributed to the raised HCG levels during 1st trimester, modulating the neuronal conductivity during that period. Conclusions: However, the non-significantly increased or similar reaction time in Group T2and T3could be attributed to increased levels of estrogen and progesterone. Hence, these hormones have neuromodulatory effect on the neuronal excitability, plasticity and excitability, though the direct effect of HCG needs further exploration.