Syphilis epidemics and human immunodeficiency virus (HIV) incidence among men who have sex with men in the United States: Implications for HIV prevention
Syphilis epidemics and human immunodeficiency virus (HIV) incidence among men who have sex with men in the United States: Implications for HIV prevention
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DOI：
10.1097/01.olq.0000180466.62579.4b
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发表时间：
2005-10-01
影响因子：
3.1
通讯作者：
Janssen, R
中科院分区：
文献类型：
--
作者：
Buchacz, K;Greenberg, A;Janssen, R
最近在美国主要城市的男男性行为者（MSM）中爆发梅毒，并报告了性风险行为的增加，这引起了人们对人类免疫缺陷病毒（HIV）传播可能增加的担忧。大多数患有早期梅毒的MSM是HIV感染者;在初步研究中，他们中最近感染HIV的比率也很高。然而，来自旧金山弗朗西斯科、洛杉矶和西雅图-金郡的数据表明，在梅毒爆发期间，在选定的大型公共场所寻求HIV检测的MSM中，HIV发病率没有时间上的增加。由于大多数艾滋病发病率和行为数据来自大都市地区，有大量的同性恋人口和完善的艾滋病流行，我们不知道在全国范围内，MSM中的艾滋病感染率在梅毒爆发期间是否增加，减少或稳定。需要进一步研究艾滋病流行成熟度不同的大城市和小城市的艾滋病发病率。还需要全面和综合的艾滋病毒/性传播疾病预防和控制工作，以阻止梅毒的传播，减少艾滋病毒在男同性恋和双性恋男子中的传播。
Recent outbreaks of syphilis among men who have sex with men (MSM) in major cities in the United States and reported increases in sexual risk behavior have raised concerns about potential increases in human immunodeficiency virus (HIV) transmission. The majority of MSM who have early syphilis are HIV infected; in preliminary studies, rates of recent HIV infection among them are also high. Data from San Francisco, Los Angeles, and Seattle-King County, however, suggest no temporal increases in HIV incidence among MSM seeking HIV testing at select large public sites during the syphilis outbreaks. Because most HIV incidence and behavioral data are from large metropolitan areas with large gay populations and well-established HIV epidemics, we do not know Whether, nationally, incidence of HIV infection among MSM has been increasing, decreasing, or stable during syphilis outbreaks. Further studies of HIV incidence in larger and smaller cities with different maturities of HIV epidemic are warranted. Comprehensive and integrated HIV/STD prevention and control efforts are also needed to halt the spread of syphilis and reduce HIV transmission among gay and bisexual men.