Risk factors for human T cell lymphotropic virus type II infection among the Guaymi Indians of Panama.
Risk factors for human T cell lymphotropic virus type II infection among the Guaymi Indians of Panama.
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巴拿马瓜伊米印第安人 II 型人类 T 细胞淋巴细胞病毒感染的危险因素。
DOI：
10.1086/314916
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发表时间：
1999
期刊：
影响因子：
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通讯作者：
Giusti,RM
中科院分区：
文献类型：
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作者：
Maloney,EM;Armien,B;Gracia,F;Castillo,L;Kruger,H;Levin,A;Levine,PH;Kaplan,JE;Blattner,WA;Giusti,RM
为了研究人类T细胞嗜淋巴病毒II型(HTLV-II)感染的危险因素，在巴拿马的瓜伊米印第安人中进行了一项病例对照研究。在女性中，HTLV-II血清阳性与早期性行为(⩽13年对15年；优势比[OR]2.50；95%可信区间[CI]1.11-6.14)和终身性伴侣数量有关。一个伴侣的血清阳性风险增加了30%(OR，1.30；CI，1.05-1.64)，并且风险随着伴侣数量的增加而增加。类似的风险与长期性关系的数量有关。在男性中，性行为与HTLV-II血清阳性有关(OR，1.68；CI，1.04-2.72)。这些数据支持性传播在HTLV-II感染中的作用。在男性中观察到的血清阳性与传统村庄主要居住地的关系(OR，3.75；CI，1.02-15.38)和缺乏正规教育(0vs.>；6年[OR，3.89；CI，1.67-9.82])可能反映了与文化适应相关的性行为的差异。
To examine risk factors for human T cell lymphotropic virus type II (HTLV-II) infection, a case-control study was conducted among the Guaymi Indians of Panama. In females, HTLV-II seropositivity was associated with early sexual intercourse (⩽13 vs. >15 years; odds ratio [OR], 2.50; 95% confidence interval [CI], 1.11–6.14) and number of lifetime sex partners. One partner increased risk of seropositivity by 30% (OR, 1.30; CI, 1.05–1.64), and risk increased with number of partners. Similar risk was associated with number of long-term sexual relationships. Among males, intercourse with prostitutes was associated with HTLV-II seropositivity (OR, 1.68; CI, 1.04–2.72). These data support a role for sexual transmission in HTLV-II infection. Association of seropositivity with primary residence in a traditional village (OR, 3.75; CI, 1.02–15.38) and lack of formal education (0 vs. >6 years [OR, 3.89; CI, 1.67–9.82]) observed in males may reflect differences in sexual practices associated with acculturation.