Acid-amide intermolecular hydrogen bonding
Acid-amide intermolecular hydrogen bonding
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DOI：
10.1021/ja963416e
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发表时间：
1997-04-23
影响因子：
15
通讯作者：
Lightner, DA
中科院分区：
文献类型：
--
作者：
Wash, PL;Maverick, E;Lightner, DA
一个具有7个吡啶酮末端的2，2-二甲基丁炔酸（1）在分子识别中作为其自身互补物，在酰胺基和羧酸基之间通过氢键形成nn个分子间氢键二聚体。通过X射线衍射、H-1-NMR实验和蒸气压渗透压测定法在1的晶体中发现二聚体，通过FAB-MS在气相中发现二聚体。
A 2,2-dimethylbutynoic acid with 7 pyridone terminus (1) acts as its self-complement in molecular recognition to form nn intermolecularly hydrogen-banded dimer with hydrogen bonding between the amide and carboxylic acid group. The dimer is found in crystals of 1 by X-ray diffraction, chloroform solution by H-1-NMR experiments and Vapor pressure osmometry, and in the gas phase by FAB-MS.