Diagnostics of spontaneous cough in childhood asthma - Results of continuous tracheal sound recording in the homes of children
Diagnostics of spontaneous cough in childhood asthma - Results of continuous tracheal sound recording in the homes of children
复制标题
DOI：
10.1378/chest.113.1.50
复制
发表时间：
1998-01-01
期刊：
影响因子：
9.6
通讯作者：
Rijssenbeek-Nouwens, LHM
中科院分区：
文献类型：
--
作者：
Rietveld, S;Rijssenbeek-Nouwens, LHM
自发性咳嗽是一种对儿童哮喘具有弥漫性诊断意义的症状，医生无法获得咳嗽的存在/频率与哮喘其他症状之间的相互关系的信息。在60名哮喘儿童和30名非哮喘儿童的家中，分别在72小时和24小时连续记录气管音。咳嗽的存在和频率以及喘息的存在被受过训练的检查者吓到了。当无法获得呼气峰流速（PEF）值时，使用哮鸣音指示气道阻塞，每4小时评估一次PEF和自我报告的呼吸困难。结果表明，哮喘患者在急性发作期咳嗽次数明显多于对照组，而在缓解期则无明显差异。咳嗽对喘息的诊断敏感性最高为72%，对PEF下降> 20%的诊断敏感性最高为69%。然而，诊断特异性很差，喘息为41%，PEF降低> 20%为34%。咳嗽和呼吸困难是独立的，3名儿童在急性发作期间没有咳嗽，在2名儿童中观察到持续的、孤立的咳嗽。得出的结论是，自发性咳嗽是哮喘急性发作的适度预测，但不是哮喘诊断或哮喘严重程度的预测。
Spontaneous cough is a symptom with diffuse diagnostic significance for childhood asthma, Information on the interrelations between presence/frequency of cough and other symptoms of asthma are not available to the physician, Tracheal sounds were continuously recorded in the homes of 60 children with and 30 without asthma, at 72 and 24 h, respectively. Presence and frequency-of cough and presence of wheeze were scared by trained examiners. Wheeze was used to indicate airway obstruction during hours when peak expiratory flow (PEF) values were not available, PEF and self-reported dyspnea were assessed every 4 h. Results showed that asthmatics coughed significantly more often than control subjects during exacerbations, but not during remission, The highest diagnostic sensitivity percentages of cough were 72% for wheeze and 69% for a reduction in PEF >20%. However, the diagnostic specificity was poor, 41% for wheeze and 34% for a reduction in PEF >20%. Cough and dyspnea were independent, Three children did not cough during exacerbations, Persistent, isolated cough was observed in two children, It was concluded that spontaneous cough is modestly predictive of asthmatic exacerbations, but: not of diagnosis of asthma or severity of asthma.