LONG-TERM CLINICAL AND EEG CHANGES IN PATIENTS WITH EPILEPSY
LONG-TERM CLINICAL AND EEG CHANGES IN PATIENTS WITH EPILEPSY
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DOI：
10.1001/archneur.1985.04060030027006
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发表时间：
1985-01-01
影响因子：
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通讯作者：
HUGHES, JR
中科院分区：
文献类型：
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作者：
HUGHES, JR
通过1645次脑电描记，研究了15到40年间脑电发作和临床发作的变化。其他类型之前最常见的阵发性发作是额叶病灶，其他类型之后是颞叶病灶。大多数模式在6-8年内发生了变化，这些脑电变化准确地预测了后来的临床发作类型。大多数患者表现为颞叶尖峰。与单侧颞叶病灶相比，双侧颞叶病灶的发生率随着年龄的增长而增加，每年几乎增加1%；34%的患者出现双侧颞叶病灶的临床表现。右侧病灶显示双侧的时间通常是左侧病灶的两倍以上；所有来自颞区的改变都比来自矢状面旁区域的改变需要更短的发展时间。大脑半球内最常见的变化是侧向移位；在统计学上，前向移位并不比后向移位更常见。
Changes during a 15- to 40-yr period were studied in EEG paroxysms and clinical seizures on 1645 EEG tracings. The most common paroxysm before other patterns was the frontal focus and after other patterns was the temporal focus. Most patterns changed in 6-8 yr and these EEG changes accurately predicted the type of later clinical attacks. The majority of patients manifested a temporal spike. The incidence of bilateral foci, as opposed to unilateral temporal foci, increased with age at a rate of almost 1% per yr; the clinical expression of developing bilateral temporal foci was seen in 34% of the patients. Right-sided foci usually required more than twice as much time to manifest bilaterality than did left-sided foci; all changes from temporal areas required shorter development times than those from parasagittal areas. The most common intrahemispheric change was lateral; anterior migration was not statistically more common than posterior migration.