The population dynamics of maternal-effect selfish genes.
The population dynamics of maternal-effect selfish genes.
复制标题
母性效应自私基因的种群动态。
DOI：
10.1093/genetics/138.4.1309
复制
发表时间：
1994
期刊：
影响因子：
3.3
通讯作者：
Beeman,RW
中科院分区：
文献类型：
--
作者：
Wade,MJ;Beeman,RW
我们使用人口遗传学的方法来描述预期的人口动态的自私基因染色体因子，美狄亚（母效应显性胚胎逮捕），最近发现在面粉甲虫，属赤拟谷盗。在没有对总繁殖力的有害影响的情况下，美狄亚因子传播到固定的所有程度的母亲效应致死率大于零，传播率与母亲效应的强度成正比。当数量稀少时，传播速度非常慢，大约是频率平方p2的数量级，但是当在家族水平上存在密度调节时，传播速度可以加快到p的数量级，这是已知的面粉甲虫的一些遗传品系。当美狄亚对繁殖力有普遍的有害影响时，除了基因型特异性母体效应外，影响所有后代基因型，那么稳定的内部多态性是可能的。内部平衡的位置和丢失或固定的概率对这些繁殖力效应的显性程度敏感。
We use population genetic methods to describe the expected population dynamics of the selfish-gene chromosomal factor, Medea (maternal-effect dominant embryonic arrest), recently discovered in flour beetles, genus Tribolium. In the absence of deleterious effects on gross fecundity, Medea factors spread to fixation for all degrees of maternal-effect lethality greater than zero and the rate of spread is proportional to the strength of the maternal-effect. The rate of spread when rare is very slow, on the order of the frequency squared p2, but this can be accelerated to order p when there is density regulation at the level of families as is known to occur for some genetic strains of flour beetles. When there are general deleterious effects of Medea on fecundity, affecting all offspring genotypes in addition to the genotype-specific maternal effect, then a stable interior polymorphism is possible. The location of the interior equilibrium and the probability of loss or fixation are sensitive to the degree of dominance of these fecundity effects.