Food allergens in mattress dust in Norwegian homes - a potentially important source of allergen exposure
Food allergens in mattress dust in Norwegian homes - a potentially important source of allergen exposure
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DOI：
10.1111/cea.12231
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发表时间：
2014-01-01
影响因子：
6.1
通讯作者：
Lovik, M.
中科院分区：
文献类型：
--
作者：
Bertelsen, R. J.;Faeste, C. K.;Lovik, M.
研究背景食物过敏原致敏和食物过敏反应主要是由摄入过敏原引起的，但也可通过呼吸道或皮肤接触而发生。关于在家庭环境中暴露于食物过敏原的情况知之甚少。这项研究的目的首先是描述从鱼、蛋、牛奶、从13岁的家庭收集的床垫灰尘和花生-方法采用斑点杂交法检测床垫中食物过敏原，并对10名老年人进行了调查挪威奥斯陆143户家庭的灰尘。我们分析了家庭特征（收集的家长问卷调查和研究技术人员）和食物过敏原之间的关联，多元回归models.ResultsFish过敏原检测到46%，花生41%，牛奶39%，鸡蛋过敏原在22%的床垫灰尘样本，只有三个样本中没有这些过敏原。所有四种食物过敏原在小住宅的床垫中检测到的频率更高（
BackgroundSensitization to food allergens and food allergic reactions are mostly caused by ingesting the allergen, but can also occur from exposure via the respiratory tract or the skin. Little is known about exposure to food allergens in the home environment.ObjectiveThe objective of this study was firstly to describe the frequency of detection of allergens from fish, egg, milk, and peanut in mattress dust collected from homes of 13-year-old adolescents and secondly to identify home characteristics associated with the presence of food allergen contamination in dust.MethodsFood allergens were measured by dot blot analysis in mattress dust from 143 homes in Oslo, Norway. We analysed associations between home characteristics (collected by parental questionnaires and study technicians) and food allergens by multivariate regression models.ResultsFish allergen was detected in 46%, peanut in 41%, milk in 39%, and egg allergen in 22% of the mattress dust samples; only three samples contained none of these allergens. All four food allergens were more frequently detected in mattresses in small dwellings (