Cigarette smoking and the risk of ovarian cancer in the Japanese population: Findings from the Japanese Collaborate Cohort study
Cigarette smoking and the risk of ovarian cancer in the Japanese population: Findings from the Japanese Collaborate Cohort study
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DOI：
10.1111/j.1447-0756.2005.00261.x
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发表时间：
2005-04-01
影响因子：
1.6
通讯作者：
Tamakoshi, A
中科院分区：
文献类型：
--
作者：
Niwa, Y;Wakai, K;Tamakoshi, A
目的：许多关于吸烟与卵巢癌风险之间关系的研究得出了不一致的结果。在这里，我们调查了这种关系，从日本合作队列研究的癌症风险评估，在1988年开始的数据。方法：一个自我管理的问卷调查吸烟习惯和其他癌症的危险因素，完成了34 639名日本妇女。经过7.6年的随访，39例卵巢癌可供分析。考克斯比例风险模型被用来计算相对危险度（RR），并调整混杂founders.Results：相对于那些从未吸烟，卵巢癌的RR为1.63（95%置信区间[CI] = 0.21-12.50）为前吸烟者和2.27（95%CI = 0.85-6.08）为当前吸烟者。在目前吸烟者中，RR为1.48（95%CI = 0.20-10.92），在吸烟女性中为5.56（95%CI = 1.68-19.06）和1.86（95%CI = 0.25-14.30
Aim: The many studies into the relation between cigarette smoking and the risk of ovarian cancer have produced inconsistent results. Here we investigated this relation using data from the Japan Collaborative Cohort Study for Evaluation of Cancer Risk, initiated in 1988.Methods: A self-administered questionnaire on smoking habits and other risk factors for cancer was completed by 34 639 Japanese women. After 7.6 years of follow up, 39 cases of ovarian cancer were available for analyses. Cox proportional-hazards models were used to compute relative risks (RR) and to adjust for confounders.Results: Relative to those who had never smoked, the RR of ovarian cancer were 1.63 (95% confidence interval [CI] = 0.21-12.50) for former smokers and 2.27 (95% CI = 0.85-6.08) for current smokers. Among current smokers, the RR were 1.48 (95% CI = 0.20-10.92), 5.56 (95% CI = 1.68-19.06), and 1.86 (95% CI = 0.25-14.30) among women who smoked