Combatting Antibiotic Resistance Together: How Can We Enlist the Help of Industry?
Combatting Antibiotic Resistance Together: How Can We Enlist the Help of Industry?
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DOI：
10.3390/antibiotics7040111
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发表时间：
2018-12-01
影响因子：
4.8
通讯作者：
Harbarth, Stephan
中科院分区：
文献类型：
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作者：
Edwards, Suzanne E.;Morel, Chantal M.;Harbarth, Stephan
抗生素的开发需要通过新的财政刺激来支持，包括公共部门的帮助。为了换取公众的支持，应该要求工业界尽其所能，帮助遏制抗生素的不当使用。这项工作讨论了工业界对抗生素消费产生重要影响的关键领域，以及可以与财政激励措施一起达成协议的领域，即使是那些旨在刺激早期研究的领域。只要传统的以单位销售为基础的抗生素商业模式仍然存在，盈利激励措施就可能破坏以可持续方式销售和利用抗生素的努力。在短期内，当我们试图就如何最好地修复市场达成共识时，我们需要采取措施防止重大的过度销售和不适当的促销，特别是对于进入市场的急需的新抗生素。本文探讨了制药行业如何帮助支持可持续的抗生素使用，同时我们寻找更长期，建设性，互利的方式来组织市场。
The development of antibiotics needs to be supported through new financial stimuli, including help from the public sector. In exchange for public support, industry should be asked to do what is in their power to help curb the inappropriate use of antibiotics. This work discusses key areas through which industry has an important influence on antibiotic consumption and where agreements can be made alongside financial incentives, even those intended to stimulate very early research. As long as the traditional unit sale-based business model for antibiotics remains in place, profit-making incentives will likely undermine efforts to sell and utilize antibiotics in a sustainable manner. In the short-term, while we try to come to a consensus on how best to fix the market, we need measures to prevent major over-selling and inappropriate promotionespecially for new, badly needed antibiotics that reach the market. This paper explores ways in which the pharmaceutical industry could help buttress sustainable antibiotic use while we search for more long-term, constructive, mutually-beneficial ways to organize the market.