Relationship between indoor chemical concentrations and subjective symptoms associated with sick building syndrome in newly built houses in Japan
Relationship between indoor chemical concentrations and subjective symptoms associated with sick building syndrome in newly built houses in Japan
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DOI：
10.1007/s00420-009-0475-9
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发表时间：
2010-02-01
影响因子：
3
通讯作者：
Kishi, Reiko
中科院分区：
文献类型：
--
作者：
Takigawa, Tomoko;Wang, Bing-Ling;Kishi, Reiko
本研究探讨化学物质与日本新居居民病态建筑症候群（SBS）型症状之间的可能关联。我们随机抽取了5709栋新建的传统住宅。最终，425户1479名居民完成了问卷调查，并同意在其家中进行室内醛类和挥发性有机化合物（VOCs）的环境监测。如果居民抱怨至少有一种SBS相关症状，他们就被归类为患有SBS。采用多元logistic回归分析筛选预测SBS症状的化学因素。大约14%的受试者患有SBS。在单变量分析中，许多醛类和挥发性有机化合物是光学、鼻腔和常规症状的相关因素。在对其他可能的危险因素进行调整后，甲醛剂量依赖性显示为SBS的重要危险因素。几种化学物质有与SBS症状相关的倾向。在日本新建房屋中检测到的化学物质往往会增加SBS患者主观症状的风险。
This study explored possible associations between chemical substances and sick building syndrome (SBS)-type symptoms of residents living in new houses in Japan.We randomly sampled 5,709 newly built conventional homes. In the end, 1,479 residents in 425 households completed a questionnaire survey and agreed to environmental monitoring for indoor aldehydes and volatile organic compounds (VOCs) to be conducted in their homes. If the residents had complained about at least one SBS-related symptom, they were classified as suffering from SBS. Multiple logistic regression analysis was used to select predictive chemical factors of SBS symptoms.About 14% of the subjects suffered from SBS. Many aldehydes and VOCs were associated factors of optical, nasal, and gular symptoms in univariate analysis. After adjustment for other possible risk factors, formaldehyde dose-dependently showed to be a significant risk factor for SBS. Several chemicals had tendency to be associated with SBS symptoms.Chemicals detected in Japanese newly built houses tend to increase the risk of subjective symptoms in residents suffering from SBS.