Total synthesis of (-)-conocarpan and assignment of the absolute configuration by chemical methods
Total synthesis of (-)-conocarpan and assignment of the absolute configuration by chemical methods
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DOI：
10.1039/b704211f
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发表时间：
2007-01-01
影响因子：
4.9
通讯作者：
Stoffman, Elia J. L.
中科院分区：
文献类型：
--
作者：
Clive, Derrick L. J.;Stoffman, Elia J. L.
（-）- conocarpan(1)采用基于自由基环化的方法合成，并通过化学降解建立绝对构型；根据后来对2,3-二氢苯并呋喃的热带学研究，原来的2R， 3r分配到(+)-康卡潘应该被颠倒。
(-)-Conocarpan (1) was synthesized by a method based on radical cyclization, and the absolute configuration was established by chemical degradation; the original 2R,3R-assignment to (+)-conocarpan should be reversed, as suggested by a later chiroptical study of model 2,3-dihydrobenzofurans.