The concentrations of retinol-binding protein, prealbumin, and transferrin in the sera of newly delivered mothers and children of various ages.

The concentrations of retinol-binding protein, prealbumin, and transferrin in the sera of newly delivered mothers and children of various ages.
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不同年龄段的初产母亲和儿童血清中视黄醇结合蛋白、前白蛋白和转铁蛋白的浓度。

DOI:
10.1080/00365517509095782
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发表时间:
1975
影响因子:
2.1
通讯作者:
T. Berg
T. Berg
中科院分区:
医学4区
文献类型:
--
作者:
Anders Vahlquist;Lars Rask;Per A. Peterson;T. Berg

文献摘要

被引文献

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检查了 50 名足月新生儿的脐带血和 226 名年龄从 6 周到 16 岁不等的儿童的毛细血管或静脉血中的视黄醇结合蛋白 (RBP)、前白蛋白和转铁蛋白的含量。新生儿中三种蛋白质的平均水平分别为 21 微克/毫升、128 微克/毫升和 1.65 毫克/毫升。相应的母体水平为 39 微克/毫升和 3.2 毫克/毫升。母亲和新生儿的配对血清值显示 RBP 和前白蛋白具有相关性,但与转铁蛋白无关。出生时的 RBP 水平较低(约为非孕妇的 50%),在头 6 个月内迅速上升,最高达到 31 微克/毫升,但此后下降到平均水平约 26 微克/毫升,一直维持到青春期,逐渐达到成人值。在血清中,前白蛋白水平显示出类似的发展,而转铁蛋白值早在 2 岁时就达到了恒定的成人水平。
Umbilical-cord blood from 50 full-term newborns and capillary or venous blood from 226 children varying in age from 6 weeks to 16 years was examined for content of retinol-binding protein (RBP), prealbumin, and transferrin. The mean levels of the three proteins in the newborns were 21 mug/ml, 128 mug/ml, and 1.65 mg/ml, respectively. The corresponding maternal levels were 39 mug/ml, and 3.2 mg/ml. Paired serum values of mothers and newborns showed a correlation for both RBP and prealbumin but not for transferrin. The low levels of RBP at birth (about 50 per cent of that of nonpregnant women) increased rapidly over the first 6 months to a maximum of 31 mug/ml but declined thereafter to a mean level of about 26 mug/ml, which was maintained until the age of puberty when adult values were gradually attained. In serum, the prealbumin levels showed a similar development, whereas the transferrin values reached constant adult levels as early as 2 years of age.