Organization of horizontal axons in the inferior temporal cortex and primary visual cortex of the macaque monkey.
Organization of horizontal axons in the inferior temporal cortex and primary visual cortex of the macaque monkey.
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DOI：
10.1093/cercor/bhi067
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发表时间：
2005-12
期刊：
影响因子：
3.7
通讯作者：
H. Tanigawa;Quanxin Wang;I. Fujita
中科院分区：
文献类型：
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作者：
H. Tanigawa;Quanxin Wang;I. Fujita
我们研究了猴腹侧视觉皮层通路中两个不同层次的水平连接组织，即下颞叶皮层（TE）和初级视觉皮层（V1）。在第2层和第3层注射顺行示踪剂后，TE中标记水平侧支的末端簇（“斑块”）出现在距离注射部位8mm的不同距离上，而V1中清晰的斑块仅分布在2mm范围内。与V1相比，TE斑块的大小和间距更大，更不规则。随着距离注射部位的远近，V1斑块的标记强度急剧下降。这种趋势在TE中不太明显；在距离较远的地点，除了标记较弱的斑块外，还存在一些标记较密的斑块。虽然注射到这两个区域会导致斑块的拉长，但对于相同大小的注射，TE的各向异性比V1更大。双示踪剂注射和大剂量注射进一步显示，与V1相比，TE的邻近部位具有空间上不同的水平投射。水平连接的这些区域特异性特征可能导致TE和V1在视觉信息处理上的差异。
We investigated the organization of horizontal connections at two distinct hierarchical levels in the ventral visual cortical pathway of the monkey, the inferior temporal (TE) and primary visual (V1) cortices. After injections of anterograde tracers into layers 2 and 3, clusters of terminals ('patches') of labeled horizontal collaterals in TE appeared at various distances up to 8 mm from the injection site, while in V1 clear patches were distributed only within 2 mm. The size and spacing of these patches in TE were larger and more irregular than those observed in V1. The labeling intensity of patches in V1 declined sharply with distance from the injection site. This tendency was less obvious in TE; a number of densely labeled patches existed at distant sites beyond weakly labeled patches. While injections into both areas resulted in an elongated pattern of patches, the anisotropy was greater in TE than in V1 for injections of a similar size. Dual tracer injections and larger-sized injections further revealed that the adjacent sites in TE had spatially distinct horizontal projections, compared to those in V1. These area-specific characteristics of the horizontal connections may contribute to the differences in visual information processing of TE and V1.