of Birmingham Using Discrete Multi-Physics for studying the dynamics of emboli in flexible venous valves
of Birmingham Using Discrete Multi-Physics for studying the dynamics of emboli in flexible venous valves
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伯明翰大学使用离散多物理场研究柔性静脉瓣膜中栓塞的动力学
DOI：
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发表时间：
2018
期刊：
影响因子：
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通讯作者：
A. Alexiadis
中科院分区：
文献类型：
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作者：
M. Ariane;D. Vigolo;A. Brill;F. G. B. Nash;M. Barigou;A. Alexiadis
8栓子是血凝块的一部分，可以卡在各种器官的脉管系统中（最常见的是肺），并导致其功能障碍甚至死亡。在这项工作中，使用数学建模，在双静脉瓣膜系统中研究了不同类型的栓塞状结构。该模型采用完全拉格朗日离散多物理技术12实现，并且流动由柔性壁控制。该研究显示了瓣膜周围流动中自由栓子的不同直径13和长度的影响。栓塞物14的存在强烈地影响静脉瓣膜中的流体和小叶的动力学，并且栓塞物在瓣膜腔室中的持久性与其长度密切相关。16
8 Emboli, which are parts of blood clots, can be stuck in the vasculature of various organs (most 9 frequently, lungs) and cause their malfunction or even death. In this work, using mathematical 10 modelling, different types of emboli-like structures are studied in a double venous valve 11 system. The model is implemented with a fully Lagrangian Discrete Multi-Physics technique 12 and the flow is governed by flexible walls. The study shows the effect of different diameters 13 and lengths of a free embolus in the flow surrounding the valve. The presence of an embolus 14 strongly affects the dynamics of both the fluid and the leaflets in venous valves and the 15 permanence of the embolus in the valve chamber is narrowly linked with its length. 16
影响因子：
20.1
作者：
Diamond SL
通讯作者：
Diamond SL