Bilateral amygdala damage impairs the acquisition and use of common ground in social interaction.
Bilateral amygdala damage impairs the acquisition and use of common ground in social interaction.
复制标题
双侧杏仁核损伤会损害社交互动中共同点的获取和使用。
DOI：
10.1037/a0021123
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发表时间：
2011
期刊：
影响因子：
2.4
通讯作者：
Tranel,Daniel
中科院分区：
文献类型：
--
作者：
Gupta,Rupa;Duff,MelissaC;Tranel,Daniel
目的：发展“共同点”，或共享信息的相互知识，被认为需要基于语言信息和非语言社会和情感信号更新他人思想和知识的心理表征的能力，以促进经济交流。就像其他形式的日常社会交流一样，共同基础的发展可能需要多种神经系统支持的多种认知过程的协调。在这里，我们研究杏仁核对这些过程的贡献。方法：SM，一名患有完全性、局灶性、双侧杏仁核损伤、社交和情绪处理缺陷的患者，与5名健康的对照者，每人与一名熟悉的伴侣进行互动。我们调查了参与者在24个动态协作互动中开发和使用参考标签的能力。参与者口头指导他们的搭档如何排列一组12个抽象的七巧板，同时被一个低屏障隔开，让他们看到彼此，但隐藏他们的七巧板。结果：与比较参与者相比，SM表现出跨试验的学习率受损，并且在交互过程中产生的标签没有显示出典型的简化。对SM的互动话语和社会行为的详细分析表明，她的换位思考能力受损，或者可以解释为“心智理论”的缺陷，表现为异常的“语言使用”。结论：这些结果支持这样的结论，即杏仁核作为一个对社会和情绪处理至关重要的结构，在获得和使用共同点以及更广泛的社会交流中起着重要作用。
Objective: The development of “common ground,” or mutual knowledge of shared information, is believed to require the ability to update a mental representation of another person's thoughts and knowledge based on verbal information and nonverbal social and emotional signals, to facilitate economical communication. As in other forms of everyday social communication, the development of common ground likely requires the orchestration of multiple cognitive processes supported by various neural systems. Here, we investigate the contribution of the amygdala to these processes. Method: SM, a patient with complete, focal, bilateral amygdala damage, and deficits in social and emotional processing, and five healthy comparison participants, each interacted with a familiar partner. We investigated the participants' ability to develop and use referential labels across 24 dynamic, collaborative interactions. Participants verbally directed their partner how to arrange a set of 12 abstract tangrams while separated by a low barrier, allowing them to see each other but hiding their tangrams. Results: In contrast to comparison participants, SM exhibited an impaired rate of learning across trials and did not show the typical simplification in the labels generated during the interactions. Detailed analyses of SM's interactional discourse and social behavior suggested that she has impaired perspective-taking or what can be interpreted as deficient “theory of mind,” manifested in abnormal “language-in-use.” Conclusions: These results support the conclusion that the amygdala, a structure critical for social and emotional processing, plays an important role in the acquisition and use of common ground and in social communication more broadly.