Integrating biological data -: the Distributed Annotation System
Integrating biological data -: the Distributed Annotation System
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DOI：
10.1186/1471-2105-9-s8-s3
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发表时间：
2008-01-01
影响因子：
3
通讯作者：
Prlic, Andreas
中科院分区：
文献类型：
--
作者：
Jenkinson, Andrew M.;Albrecht, Mario;Prlic, Andreas
背景：分布式注释系统（DAS）是一种被广泛采用的协议，用于动态整合来自不同地理位置的各种生物数据。DAS不断扩展其适用性，并针对整合生物信息学面临的新挑战而不断发展。
结果：在此我们描述了DAS的各种基础设施组件，并提出了DAS规范的一个新的扩展版本。1.53E版本包含了一些近期的发展成果，包括其扩展以服务于新的数据类型以及一个蛋白质特征的本体。
结论：我们对DAS协议的扩展促进了新数据类型的整合，我们对现有DAS基础设施的改进解决了近期面临的挑战。可用数据源数量的稳步增加表明DAS协议得到了进一步的采用。
Background: The Distributed Annotation System (DAS) is a widely adopted protocol for dynamically integrating a wide range of biological data from geographically diverse sources. DAS continues to expand its applicability and evolve in response to new challenges facing integrative bioinformatics.Results: Here we describe the various infrastructure components of DAS and present a new extended version of the DAS specification. Version 1.53E incorporates several recent developments, including its extension to serve new data types and an ontology for protein features.Conclusion: Our extensions to the DAS protocol have facilitated the integration of new data types, and our improvements to the existing DAS infrastructure have addressed recent challenges. The steadily increasing numbers of available data sources demonstrates further adoption of the DAS protocol.