CORRELATION OF GLUCOSE REGULATION AND HEMOGLOBIN-A-IC IN DIABETES-MELLITUS
CORRELATION OF GLUCOSE REGULATION AND HEMOGLOBIN-A-IC IN DIABETES-MELLITUS
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DOI：
10.1056/nejm197608192950804
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发表时间：
1976-01-01
影响因子：
158.5
通讯作者：
CERAMI, A
中科院分区：
文献类型：
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作者：
KOENIG, RJ;PETERSON, CM;CERAMI, A
对5名住院糖尿病患者的Hb AIa + Ib和Hb AIc水平升高情况进行了研究，以确定糖尿病控制情况的改变是否会导致这些血红蛋白水平的平行变化。在糖尿病控制之前，所有患者的平均空腹血糖为343毫克/分升（280 - 450），Hb AIc浓度为9.8%（6.8 - 12.1）。在最佳糖尿病控制期间，血糖浓度为84毫克/分升（70 - 100），Hb AIc浓度为5.8%（4.2 - 7.6）。Hb AIc浓度似乎能最好地反映过去数周乃至数月的平均血糖浓度。定期监测Hb AIc水平为记录糖尿病患者糖代谢的控制程度提供了一种有用的方法，并提供了一种评估碳水化合物控制与后遗症发展之间关系的手段。
The increased levels of Hb AIa+Ib and Hb AIc were studied in 5 hospitalized diabetic patients to determine whether changes in diabetic control would cause parallel changes in the levels of these hemoglobins. Before control of diabetes the mean fasting blood sugar for all patients was 343 mg/dl (280-450), and Hb AIc concentration 9.8% (6.8-12.1). During optimal diabetic control the blood sugar concentration was 84 mg/dl (70-100), and Hb AIc concentration 5.8% (4.2-7.6). Hb AIc concentration appears to reflect the mean blood sugar concentration best over previous weeks to months. The periodic monitoring of Hb AIc levels provides a useful way of documenting the degree of control of glucose metabolism in diabetic patients and provides a means whereby the relation of carbohydrate control to the development of sequelae can be assessed.