Comparative Study of Drainage and Antibiotics versus Drainage Only in the Management of Primary Subcutaneous Abscesses
Comparative Study of Drainage and Antibiotics versus Drainage Only in the Management of Primary Subcutaneous Abscesses
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DOI：
10.1089/sur.2017.225
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发表时间：
2018-04-01
影响因子：
2
通讯作者：
Anaya, Luis
中科院分区：
文献类型：
--
作者：
Lopez, Julio;Gomez, Gilberto;Anaya, Luis
背景：皮肤和软组织感染是急诊科和医务室处理的常见问题。在皮肤脓肿切开和引流后，处方抗生素是常规做法。然而，目前的证据并不支持在手术清创后处方口服抗生素。本研究的目的是确定皮肤脓肿引流后抗生素的实际作用。患者和方法：这是一项对接受皮下脓肿切开引流（I&D）的患者进行的前瞻性研究。患者在I&D后被随机分配接受抗生素（组1）或安慰剂（组2）。主要终点为第7天脓肿消退率。次要终点是第七天的疼痛和伤口完全愈合的总时间。P值
Background: Skin and soft tissue infections are common problems dealt with in emergency departments and medical offices. It is routine practice to prescribe antibiotic agents after incision and drainage of cutaneous abscesses. However, current evidence does not support prescribing oral antibiotic agents after surgical debridement. The aim of the present study was to determine the actual role of antibiotic agents after drainage of cutaneous abscesses. Patients and Methods: This was a prospective study of patients undergoing incision and drainage (I&D) of a subcutaneous abscess. Patients were randomly assigned either to receive antibiotic agents (group 1) or placebo (group 2) after I&D. The primary end point was resolution rate of the abscess at the seventh day. Secondary end points were pain at the seventh day and total time to full healing of the wound. P value