Apolipoproteins in rat serum and renal lymph.
Apolipoproteins in rat serum and renal lymph.
复制标题
大鼠血清和肾淋巴液中的载脂蛋白。
DOI：
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发表时间：
1976
影响因子：
11.1
通讯作者：
G. Pinter
中科院分区：
文献类型：
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作者：
P. Roheim;D. Edelstein;G. Pinter
用定量免疫电泳法测定大鼠血清、血清无脂蛋白超速离心组分(密度大于1.21)和肾淋巴中载脂蛋白的浓度。A-IV和富含精氨酸的载脂蛋白在密度大于1.21的部分和肾淋巴中均存在于高浓度(大于血清浓度的18.5%)，而其他载脂蛋白在低浓度(小于血清浓度的7%)中存在。肾淋巴中的主要载脂蛋白与密度大于1.21的部分相似，但肾淋巴中的载脂蛋白组成与血清脂蛋白中的载脂蛋白组成有很大不同。某些载脂蛋白在密度大于1.21的部分和肾淋巴中的存在表明，这些载脂蛋白可能以“游离”载脂蛋白的形式存在于血液循环中。推测了这些特定载脂蛋白可能的生理重要性。
The concentration of apolipoproteins was measured by quantitative immunoelectrophoresis in rat serum, in the lipoprotein-free ultracentrifugal fraction (density greater than 1.21) of serum, and in renal lymph. The A-IV and arginine-rich apolipoproteins were present in high concentrations (greater than 18.5% of serum concentration) both in the fraction of density greater than 1.21 and in renal lymph, whereas the other apolipoproteins were found in low concentrations ( less than 7% of serum concentration). The major apolipoproteins of renal lymph were similar to those found in the fraction of density greater than 1.21; however, the apolipoproteins composition of the renal lymph was very different from the apolipoprotein composition of serum lipoproteins. The presence of certain apolipoproteins in the fraction of density greater than 1.21 and in renal lymph suggests that these apolipoproteins might be present in the circulation as "free" apolipoproteins. The possible physiological importance of these specific apolipoproteins is postulated.