Wound-bed preparation: a vital step in the healing process.
Wound-bed preparation: a vital step in the healing process.
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DOI：
10.12968/bjon.2017.26.12.s24
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发表时间：
2017-06-22
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影响因子：
--
通讯作者：
Barrett, Simon
中科院分区：
文献类型：
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作者：
Barrett, Simon
无法愈合的伤口是医疗保健系统的重大负担，据估计，在任何时候都有4-5%的成年人有问题伤口（Guest等人，2017）。研究表明，感染是未愈合伤口中最常见的并发症，它可以延长患者的治疗时间并增加资源使用（Gottrup等，2013）。伤口感染是由于患者的免疫系统和伤口状况之间的不平衡而产生的，这种不平衡随后会促进细菌增殖（Wounds UK, 2013）。它可以通过延迟伤口愈合，增加截肢和危及生命的疾病的风险以及降低生活质量来影响患者。由于抗生素耐药性的风险增加，使用抗生素治疗伤口感染的情况有所减少（Swanson等人，2014年）。因此，采用了预防和处理伤口感染的替代策略，包括伤口清创和使用局部抗菌/抗菌剂。
Non-healing wounds are a significant burden to healthcare systems, where it is estimated that 4-5% of the adult population has a problem wound at any one time ( Guest et al, 2017 ). It is suggested that infection is the most frequent complication in non-healing wounds where it can prolong patient treatment times and increase resource use ( Gottrup et al, 2013 ). Wound infection develops as a result of an imbalance between the patient's immune system and the conditions in the wound, which subsequently can promote bacterial proliferation ( Wounds UK, 2013 ). It can impact on the patient by delaying wound healing, increasing the risk of amputation and life-threatening conditions, and reducing quality of life. The use of antibiotics to treat wound infections has decreased due to the increased risk of antibiotic resistance ( Swanson et al, 2014 ). As a result alternative strategies for preventing and managing wound infection have been adopted, including wound debridement and the use of topical antiseptic/antimicrobial agents.