Vulvoldynia - Characteristics and associations with comorbidities and quality of life
Vulvoldynia - Characteristics and associations with comorbidities and quality of life
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DOI：
10.1097/01.aog.0000199951.26822.27
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发表时间：
2006-03-01
影响因子：
7.2
通讯作者：
Rhoads, George G.
中科院分区：
文献类型：
--
作者：
Arnold, Lauren D.;Bachmann, Gloria A.;Rhoads, George G.
目的：本病例-对照调查比较外阴痛女性的健康史和医疗保健使用情况，并与无妇科疼痛的对照组进行比较。方法：经临床评估诊断为外阴痛的女性和无症状对照者按年龄进行匹配，并邮寄一份保密调查，评估人口统计学、健康史、卫生保健系统使用情况和外阴痛病史。参与者都是大学医疗保健系统内的当前或以前的流动病人。结果：在寄送至有效地址的512份问卷中，70% （n = 91）的病例和72% （n = 275）的对照有应答，其中77例病例和208例对照符合入选标准。据报道，患有外阴阴唇的女性对生活质量产生了严重的负面影响，42%的人感觉无法控制自己的生活，60%的人感觉无法控制自己的身体。41%的人表示，这严重影响了他们的性生活。当单独评估合并症并根据年龄进行调整时，纤维肌痛（优势比3.84,95%可信区间1.54-9.55）和肠易激综合征（优势比3.11,95%可信区间1.60-6.05）与外阴阴道明显相关。在多变量水平上，外阴阴唇与慢性酵母菌阴道炎和尿路感染的病史相关。结论：这项调查强调了外阴阴唇相关的心理困扰，并强调了前瞻性研究的必要性，以调查慢性膀胱和阴道感染作为这种情况的病因之间的关系。此外，外阴阴唇与其他合并症的关系，如纤维肌痛和肠易激综合征，需要进一步评估。
OBJECTIVE: This case-control survey compared health history and health care use of women with vulvodynia with a control group reporting absence of gynecologic pain.METHODS: Women with a clinically assessed diagnosis of vulvodynia and asymptomatic controls were matched for age and mailed a confidential survey that evaluated demographics, health history, use of the health care system, and history of vulvoclynia. Participants were all current or former ambulatory patients within a university health care system.RESULTS: Of the 512 questionnaires mailed to valid addresses, 70% (n = 91) of cases and 72% (n = 275) of controls responded, with 77 cases and 208 controls meeting eligibility criteria. Women with vulvoclynia reported a substantial negative impact on quality of life, with 42% feeling out of control of their lives and 60% feeling out of control of their bodies. Forty-one percent indicated a severe impact on their sexual lives. When comorbidities were evaluated individually and adjusted for age, fibromyalgia (odds ratio 3.84, 95% confidence interval 1.54-9.55) and irritable bowel syndrome (odds ratio 3.11, 95% confidence interval 1.60-6.05) were significantly associated with vulvoclynia. On a multivariate level, vulvoclynia was correlated with a history of chronic yeast vaginitis and urinary tract infections.CONCLUSION: This survey highlights the psychological distress associated with vulvoclynia and underscores the need for prospective studies to investigate the relationship between chronic bladder and vaginal infections as etiologies for this condition. As well, the association of vulvoclynia with other comorbid conditions, such as fibromyalgia and irritable bowel syndrome, needs to be further evaluated.