Ruthenium-catalyzed direct oxidative alkenylation of arenes through twofold C-H bond functionalization
Ruthenium-catalyzed direct oxidative alkenylation of arenes through twofold C-H bond functionalization
复制标题
DOI：
10.1039/c2sc21524a
复制
发表时间：
2013-01-01
期刊：
影响因子：
8.4
通讯作者：
Ackermann, Lutz
中科院分区：
文献类型：
--
作者：
Kozhushkov, Sergei I.;Ackermann, Lutz
采用容易获得、选择性和相对便宜的钌催化剂，通过芳烃和杂芳烃的双碳氢键功能化直接烯烃取得了重大进展。特别是，钌（II）配合物允许具有挑战性的直接双C-H/C-H键烯化芳烃的广泛范围。这些催化剂为富电子芳烃和缺电子芳烃以及杂芳烃的C-H/C-H键功能化奠定了阶梯经济的基础，从而为不同装饰的苯乙烯提供了多种途径。
Significant progress has been accomplished in direct olefinations through twofold C-H bond functionalization of arenes and heteroarenes employing readily accessible, selective and relatively inexpensive ruthenium catalysts. Particularly, ruthenium(II) complexes have allowed challenging direct double C-H/C-H bond alkenylations of arenes with ample scope. These catalysts set the stage for step-economical C-H/C-H bond functionalization with electron-rich as well as electron-deficient arenes and heteroarenes, and, thereby, provide versatile access to diversely decorated styrenes.