Oxytocin during pregnancy and early postpartum: Individual patterns and maternal-fetal attachment

Oxytocin during pregnancy and early postpartum: Individual patterns and maternal-fetal attachment
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DOI:
10.1016/j.peptides.2007.04.016
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发表时间:
2007-06-01
期刊:
影响因子:
3
通讯作者:
Weller, Aron
Weller, Aron
中科院分区:
医学3区
文献类型:
--
作者:
Levine, Ari;Zagoory-Sharon, Orna;Weller, Aron

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催产素 (OT) 是一种纳米肽激素,在母性行为的出现中发挥着重要作用,但很少有研究检查人类在怀孕期间和产后的催产素。我们在三个时间点对健康女性进行了跟踪:妊娠早期、妊娠晚期和产后第一个月。血浆 OT 水平显示出较高的个体稳定性。三分之一的样本显示出一致的 OT 水平,而其他样本则显示出增加或减少的趋势或在怀孕后期达到峰值。从妊娠早期到妊娠晚期 OT 的增加与母婴关系的增强相关。这些数据可能有助于设定 OT 水平的标准,并强调与母婴依恋的联系。 (c) 2007 Elsevier Inc. 保留所有权利。
Oxytocin (OT), a nanopeptide hormone, plays a role in the emergence of maternal behavior, yet few studies examined OT in humans across pregnancy and the postpartum. We followed healthy women at three points: first trimester of pregnancy, third trimester, and first postpartum month. Plasma OT levels showed high individual stability. A third of the sample showed consistent OT levels, whereas others showed increasing or decreasing trends or peak in late pregnancy. The increase in OT from early to late pregnancy correlated with higher maternal-fetal bonding. These data may help set standards for OT levels and underscore links with maternal-infant attachment. (c) 2007 Elsevier Inc. All rights reserved.