Benign Sacral Metastatic Meningioma: A Rare Entity.
Benign Sacral Metastatic Meningioma: A Rare Entity.
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发表时间：
2015-06
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通讯作者：
M. Strong;J. Garces;Wendell W. Tang;M. Ware
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作者：
M. Strong;J. Garces;Wendell W. Tang;M. Ware
背景脑膜瘤是常见的颅内肿瘤，转移率低。那些确实发生转移的患者通常会表现出恶性肿瘤的组织病理学迹象。在极少数情况下，原发性和继发性肿瘤在组织学上是良性的。病例报告 我们报告一例 57 岁女性，患有组织学良性颅内脑膜瘤，并转移至骶骨。患者有颅内脑膜瘤病史较长，且多次复发。每次复发时，切除肿瘤的组织病理学检查均未显示恶性肿瘤迹象。对骶骨脑膜瘤进行活组织检查，发现组织学为良性。该患者接受了放射治疗（54 Gy，分 30 次），症状得到缓解。六个月后，患者出现左腿无力。磁共振成像显示她的颅内肿块增大，为此她接受了开颅手术切除肿瘤。病理评估显示良性脑膜瘤证据，无非典型特征。她从这次手术中恢复得很好，几周后就恢复到了基线。结论 治疗后，患者的任一部位均未出现影像学进展迹象。
BACKGROUND Meningiomas are common intracranial tumors with a low metastatic rate. Those that do metastasize often show histopathologic signs of malignancy. In rare cases, the primary and secondary tumors are histologically benign. CASE REPORT We report the case of a 57-year-old female with a histologically benign intracranial meningioma that metastasized to the sacrum. The patient had a long history of intracranial meningioma with multiple recurrences. At each recurrence, histopathologic examination of the resected tumor showed no signs of malignancy. The sacral meningioma was biopsied and found to be histologically benign. The patient was treated with radiotherapy (54 Gy in 30 fractions), and her symptoms resolved. Six months later, the patient developed left leg weakness. Magnetic resonance imaging showed growth of her intracranial mass for which she underwent a craniotomy for tumor resection. Pathologic evaluation showed evidence of benign meningioma without atypical features. She recovered well from this procedure and returned to her baseline in several weeks. CONCLUSION After treatment, the patient had no signs of radiographic progression in either location.