Relationship between self-reported childhood behavioral inhibition and lifetime anxiety disorders in a clinical sample

Relationship between self-reported childhood behavioral inhibition and lifetime anxiety disorders in a clinical sample
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DOI:
10.1002/da.20082
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发表时间:
2005-01-01
影响因子:
7.4
通讯作者:
Malhi, GS
Malhi, GS
中科院分区:
医学1区
文献类型:
--
作者:
Gladstone, GL;Parker, GB;Malhi, GS

文献摘要

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为了研究早期抑制性气质与终生焦虑障碍之间的关系,我们研究了一个没有根据共病轴I焦虑障碍选择的重度抑郁症患者样本。189名成年人(范围= 17-68岁)被转诊至三级抑郁症单位,接受了抑郁和焦虑的结构化诊断访谈,并完成了两项行为抑制的自我报告测量,行为抑制的回顾性测量(RMBI)[Gladstone and帕克,2005]和行为抑制的成人测量(AMBI)[Gladstone and帕克,2005]。患者的评分分为“低”、“中等”或“高”抑制。虽然各组在抑郁严重程度方面没有差异,但在临床诊断的非抑郁状态和首次发作的年龄方面存在差异。那些报告儿童期抑制程度高的人更有可能被诊断为社交恐惧症,这种关联与他们的AMBI评分无关。研究结果进行了讨论,根据现有的风险因素的文献和支持的假设,早期抑制气质可能是一个显着的前兆,后来的焦虑,特别是社交焦虑症。
To examine the association between an early inhibited temperament and lifetime anxiety disorders, we studied a sample of patients with major depression who were not selected on the basis of coinorbid axis I anxiety disorders. One-hundred eighty-nine adults (range = 17-68 years) referred to a tertiary depression unit underwent structured diagnostic interviews for depression and anxiety and completed two self-report measures of behavioral inhibition, the retrospective measure of behavioural inhibition (RMBI) [Gladstone and Parker, 2005] and the adult measure of bebavioural inhibition (AMBI) [Gladstone and Parker, 2005]. Patients' scores were classified into "low," "moderate," or "high" inhibition. While groups did not differ in terms of depression severity, there were differences across groups in clinically diagnosed nonmelancholic status and age of onset of first episode. Those reporting a high degree of childhood inhibition were significantly more likely to qualify for a diagnosis of social phobia, and this association was independent of their scores on the AMBI. Findings are discussed in light of the existing risk-factor literature and support the hypothesis that an early inhibited temperament may be a significant precursor to later anxiety, especially social anxiety disorder.