Measurement of placental oxygenation by transabdominal near-infrared spectroscopy
Measurement of placental oxygenation by transabdominal near-infrared spectroscopy
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DOI：
10.1055/s-2006-958155
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发表时间：
2007-03-01
影响因子：
2
通讯作者：
Kanayama, Naohiro
中科院分区：
文献类型：
--
作者：
Kawamura, Takakazu;Kakogawa, Jun;Kanayama, Naohiro
胎盘中的子宫-胎盘循环对胎儿有重要影响。近红外光谱（NIRS）是一种测量活组织血容量和氧浓度变化的无创方法。本研究的目的是利用近红外光谱监测妊娠期宫内胎儿生长受限患者胎盘组织氧指数（TOI）水平的变化。我们测量了15例正常孕妇和15例宫内生长受限患者的胎盘TOI值。所有患者均行胎盘超声检查和近红外光谱检查。IUGR组住院时TOI值为78.6 +/- 1.6 （SD）。该数值显著高于对照组（78.6 +/- 1.6 [SD] vs . 70.2 +/- 0.4 [SD]）。IUGR组分娩前TOI值为77.8±1.6 （SD）。IUGR组分娩前TOI值明显高于对照组（77.8 +/- 1.6 [SD] vs . 70.3 +/- 0.4 [SD]）。我们建议近红外光谱是一种候选的、无创的方法，用于实时评估胎盘氧动力学。在不久的将来，它可能有助于围产期医疗实践。
The uteroplacental circulation in the placenta can have a major impact on the fetus. Near infrared spectroscopy (NIRS) is the noninvasive method of measuring changes in blood volumes and oxygen concentrations in living tissue. The purpose of this study is to monitor changes in placental tissue oxygen index (TOI) levels, in patients with intrauterine fetal growth restriction during pregnancy, using NIRS. We measured placental TOI values of 15 normal pregnant woman and 15 patients with intrauterine growth restriction admitted to our hospital. The placenta was assessed by ultrasound examination and NIRS was performed on all patients. The TOI values of the IUGR group when hospitalized was 78.6 +/- 1.6 (SD). This value was significantly higher than that of the controls (78.6 +/- 1.6 [SD] versus 70.2 +/- 0.4 [SD]). And the TOI values of the IUGR group, when measured before delivery, were 77.8 +/- 1.6 (SD). The TOI values of the IUGR group before delivery were significantly higher than those of the control group (77.8 +/- 1.6 [SD] versus 70.3 +/- 0.4 [SD]). We propose that NIRS is a candidate, noninvasive method for assessing placental oxygen dynamics on a real-time basis. In the near future it may contribute to perinatal medical practice.