PTSD Symptom Severity and Emotion Regulation Strategy Use During Trauma Cue Exposure Among Patients With Substance Use Disorders: Associations With Negative Affect, Craving, and Cortisol Reactivity.
PTSD Symptom Severity and Emotion Regulation Strategy Use During Trauma Cue Exposure Among Patients With Substance Use Disorders: Associations With Negative Affect, Craving, and Cortisol Reactivity.
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DOI：
10.1016/j.beth.2017.05.005
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发表时间：
2018-01
期刊：
影响因子：
3.7
通讯作者：
Gratz KL
中科院分区：
文献类型：
--
作者：
Tull MT;Berghoff CR;Wheeless LE;Cohen RT;Gratz KL
创伤后应激障碍（PTSD）病理与物质使用障碍（SUD）的共同发生与情绪调节缺陷有关。然而，这一领域的研究通常依赖于基于特质的情绪调节措施，关于PTSD病理与使用特定情绪调节策略来应对创伤相关痛苦的关系，以及这些策略对创伤线索反应的影响的信息有限。本研究探讨创伤暴露后PTSD症状严重程度与创伤线索暴露时特定情绪调节策略的关系，以及创伤线索暴露前后PTSD症状严重程度与负面情绪、渴望和皮质醇水平变化的间接关系。研究对象为133例外伤暴露的SUD患者。参与者听了一个个性化的创伤脚本，并报告了脚本期间使用的情绪调节策略。实验前后收集了负面影响、渴望和皮质醇的数据。PTSD症状严重程度与使用适应性强（如分心）和适应性差（如抑制）的调节策略呈正相关。此外，我们还发现了PTSD症状严重程度通过适应性和非适应性情绪调节策略间接影响负性情绪和皮质醇反应的证据。讨论了研究结果的含义。
The co-occurrence of posttraumatic stress disorder (PTSD) pathology with a substance use disorder (SUD) is associated with emotion regulation deficits. However, studies in this area generally rely on trait-based emotion regulation measures, and there is limited information on the relation of PTSD pathology to the use of specific emotion regulation strategies in response to trauma-related distress among SUD patients or the consequences of these strategies for trauma cue reactivity. This study examined the relation of PTSD symptom severity to the use of specific emotion regulation strategies during trauma cue exposure among trauma-exposed SUD patients, as well as the indirect relations of PTSD symptom severity to changes in negative affect, cravings, and cortisol levels pre- to post-trauma cue exposure through different emotion regulation strategies. Participants were 133 trauma-exposed SUD patients. Participants listened to a personalized trauma script and reported on emotion regulation strategies used during the script. Data on negative affect, cravings, and cortisol were collected pre- and post-script. PTSD symptom severity related positively to the use of more adaptive (e.g., distraction) and maladaptive (e.g., suppression) regulation strategies. Moreover, evidence for the indirect effects of PTSD symptom severity on negative affect and cortisol reactivity through both adaptive and maladaptive emotion regulation strategies was found. Implications of findings are discussed.
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