Laser speckle imaging based on intensity fluctuation modulation.
Laser speckle imaging based on intensity fluctuation modulation.
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DOI：
10.1364/ol.38.001313
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发表时间：
2013-04
期刊：
影响因子：
3.6
通讯作者：
Ya-guang Zeng;Mingyi Wang;Guangping Feng;Xianjun Liang;Guojian Yang
中科院分区：
文献类型：
--
作者：
Ya-guang Zeng;Mingyi Wang;Guangping Feng;Xianjun Liang;Guojian Yang
提出了一种利用强度起伏调制（IFM）方法获得全场激光散斑微血管图像的方法。与激光散斑衬度分析不同，IFM成像对流速不敏感，可用于重建具有更高空间分辨率和信噪比的微血管图像。在小鼠耳廓上进行的在体动物实验证明IFM成像能够实现激光散斑微血管造影。
We present a method, intensity fluctuation modulation (IFM), to obtain a full-field laser speckle microvessel image. Different from laser speckle contrast analysis, IFM imaging is insensitive to flow velocity and can be used to reconstruct microvessel images with higher spatial resolution and SNR. An in vivo animal experiment on a mouse pinna is conducted to demonstrate that IFM imaging is capable of achieving laser speckle microangiography.