Granuloma annulare Pathogenesis, disease associations and triggers, and therapeutic options
Granuloma annulare Pathogenesis, disease associations and triggers, and therapeutic options
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DOI：
10.1016/j.jaad.2015.03.055
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发表时间：
2016-09-01
影响因子：
13.8
通讯作者：
Rosenbach, Misha
中科院分区：
文献类型：
--
作者：
Piette, Evan W.;Rosenbach, Misha
环状肉芽肿（GA）是一种原因不明的皮肤反应模式，具有多种先前描述的潜在疾病相关性和触发因素。本综述试图综合现有的数据，潜在的病因，审查现有的数据，潜在的GA疾病协会和工作的GA患者，并讨论了潜在的煽动触发。在最后一部分，本文描述了可用的治疗方案和支持数据，并提供了一个框架，接近GA患者的管理。前面的文章提供了一个全面的概述，现有的信息已知的临床变异，流行病学，遗传学和组织学的GA。
Granuloma annulare (GA) represents a cutaneous reaction pattern of unknown cause with a variety of previously described potential disease associations and triggers. This review attempts to synthesize the available data regarding potential etiopathogenesis, reviews the available data on potential GA disease associations and work-up indicated for patients with GA, and discusses potential inciting triggers. In the final part, this article describes the available treatments options and supporting data, and provides a framework for approaching management of patients with GA. The previous accompanying article provided a comprehensive overview of the available information known about the clinical variants, epidemiology, genetics, and histology of GA.