Psoriasis causes as much disability as other major medical diseases
Psoriasis causes as much disability as other major medical diseases
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DOI：
10.1016/s0190-9622(99)70112-x
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发表时间：
1999-09-01
影响因子：
13.8
通讯作者：
Reboussin, DM
中科院分区：
文献类型：
--
作者：
Rapp, SR;Feldman, SR;Reboussin, DM
背景资料：与其他患者群体相比，与银屑病相关的健康相关生活质量（HRQL）如何，目前尚不清楚。目的：我们描述与银屑病相关的HRQL，并将其与其他主要慢性健康状况患者的HRQL进行比较。第二个目的是确定哪些具体方面的银屑病贡献最HRQL.Methods：共有317例患者完成了非疾病特异性措施HRQL。与其他10种慢性健康状况的患者的反应进行了比较。HRQL回归评级的18个方面的银屑病。结果：银屑病患者报告减少的身体功能和精神功能相媲美，在癌症，关节炎，高血压，心脏病，糖尿病和抑郁症。结论：银屑病对HRQL的影响与其他主要内科疾病相似。银屑病的不同方面与HRQL的不同维度相关，支持多维治疗模式的需求。
Background: Little is known about how the health-related quality of life (HRQL) associated with psoriasis compares with that of other patient populations.Objective,:We describe HRQL associated with psoriasis and compare it with HRQL of patients with other major chronic health conditions. A second aim is to identify which specific aspects of psoriasis contribute most to HRQL.Methods: A total of 317 patients completed a non-disease-specific measure of HRQL. Responses were compared with those of patients with 10 other chronic health conditions. HRQL was regressed on ratings of 18 aspects of psoriasis.Results: Patients with psoriasis reported reduction in physical functioning and mental functioning comparable to that seen in cancer, arthritis, hypertension, heart disease, diabetes, and depression. Six aspects of psoriasis predicted physical functioning, and 5 different disease aspects predicted mental functioningConclusion: The impact of psoriasis on HRQL is similar to that of other major medical diseases. Different aspects of psoriasis are related to the different dimensions of HRQL supporting the need for multidimensional treatment models.