Preferential vascular-based transfer from vagina to the corpus but not to the tubal part of the uterus in postmenopausal women
Preferential vascular-based transfer from vagina to the corpus but not to the tubal part of the uterus in postmenopausal women
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DOI：
10.1093/humrep/16.7.1329
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发表时间：
2001-07-01
影响因子：
6.1
通讯作者：
Barba, B
中科院分区：
文献类型：
--
作者：
Einer-Jensen, N;Cicinelli, E;Barba, B
背景：在不孕症治疗期间阴道给药黄体酮比口服给药有治疗优势。为了证明物质在阴道到子宫的优先分布，我们研究了从阴道到子宫和直肠的冷分布。方法：在10名绝经后妇女中，将热探针插入子宫腔和距离肛门9厘米的直肠；结果：10 min后，子宫、输卵管角度下降：-0.22 +/- 0.07°c, 10（平均a SEM， n）；子宫，中腔：-1.26 +/- 0.34°，9；直肠,
BACKGROUND: Vaginal administration of progesterone during infertility treatment has therapeutic advantages over oral administration. However, the reasons for this are poorly defined, To demonstrate a preferential vagina-to-uterus distribution of substances, we investigated cold distribution from vagina to the uterus and rectum, METHOD: In 10 postmenopausal women, thermoprobes were inserted into the uterine cavity and in the rectum at 9 cm from the anus; temperatures were subsequently measured during 10 min flushing of vagina with cold saline, RESULTS: After 10 min, temperature decreased as follows: uterus, tubal angle: -0.22 +/- 0.07 degreesC, 10 (mean a SEM, n); uterus, middle cavity: -1.26 +/- 0.34 degreesC, 9; rectum,