Dynamical Transition of Collective Motions in Dry Proteins
Dynamical Transition of Collective Motions in Dry Proteins
复制标题
干蛋白质集体运动的动态转变
DOI：
10.1103/physrevlett.119.048101
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发表时间：
2017-07-25
影响因子：
8.6
通讯作者：
Hong, Liang
中科院分区：
文献类型：
--
作者：
Liu, Zhuo;Huang, Juan;Hong, Liang
Water is widely assumed to be essential for protein dynamics and function. In particular, the well-documented "dynamical" transition at similar to 200 K, at which the protein changes from a rigid, nonfunctional form to a flexible, functional state, as detected in hydrogenated protein by incoherent neutron scattering, requires hydration. Here, we report on coherent neutron scattering experiments on perdeuterated proteins and reveal that a transition occurs in dry proteins at the same temperature resulting primarily from the collective heavy-atom motions. The dynamical transition discovered is intrinsic to the energy landscape of dry proteins.
