Thiol-Based Peroxidases and Ascorbate Peroxidases: Why Plants Rely on Multiple Peroxidase Systems in the Photosynthesizing Chloroplast?
Thiol-Based Peroxidases and Ascorbate Peroxidases: Why Plants Rely on Multiple Peroxidase Systems in the Photosynthesizing Chloroplast?
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DOI：
10.14348/molcells.2016.2324
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发表时间：
2016-01
影响因子：
3.8
通讯作者：
Dietz KJ
中科院分区：
文献类型：
--
作者：
Dietz KJ
光合作用是一个非常强大的过程，允许快速调整不断变化的环境条件。有效的驯化取决于平衡的氧化还原代谢和活性氧释放的控制，活性氧释放触发信号级联和潜在的有害氧化反应。过氧化物氧还蛋白和谷胱甘肽过氧化物酶类型的硫醇过氧化物酶和抗坏血酸过氧化物酶是叶绿体的主要过氧化物解毒酶。它们使用不同的电子供体，并连接到不同的氧化还原网络。此外，过氧化物酶在氧化还原调节和逆行信号传导中起作用。质体过氧化物酶的复杂性进行了讨论的上下文中的亚细胞定位，底物的偏好，代谢偶联，蛋白质丰度，活性调节，相互作用，信号功能，和高抗氧化能力的条件要求。因此，审查提供了一个意见的优势，连接解毒过氧化物不同的酶系统和实施机制，其失活，以加强信号传播内和叶绿体。
Photosynthesis is a highly robust process allowing for rapid adjustment to changing environmental conditions. The efficient acclimation depends on balanced redox metabolism and control of reactive oxygen species release which triggers signaling cascades and potentially detrimental oxidation reactions. Thiol peroxidases of the peroxiredoxin and glutathione peroxidase type, and ascorbate peroxidases are the main peroxide detoxifying enzymes of the chloroplast. They use different electron donors and are linked to distinct redox networks. In addition, the peroxiredoxins serve functions in redox regulation and retrograde signaling. The complexity of plastid peroxidases is discussed in context of suborganellar localization, substrate preference, metabolic coupling, protein abundance, activity regulation, interactions, signaling functions, and the conditional requirement for high antioxidant capacity. Thus the review provides an opinion on the advantage of linking detoxification of peroxides to different enzymatic systems and implementing mechanisms for their inactivation to enforce signal propagation within and from the chloroplast.