Depression and Parkinson's disease: current knowledge.
Depression and Parkinson's disease: current knowledge.
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DOI：
10.1007/s11910-013-0409-5
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发表时间：
2013-12
影响因子：
5.6
通讯作者：
Marsh L
中科院分区：
文献类型：
--
作者：
Marsh L
抑郁障碍在帕金森氏病(PD)患者中很常见，并影响该疾病的许多其他临床方面。抑郁障碍除了导致固有的情绪困扰外，还会对帕金森病患者的生活质量、运动和认知障碍、功能障碍和其他精神并发症产生负面影响。对帕金森病抑郁的病理生理学知识仍然有限。然而，临床研究证明了药物和心理疗法对帕金森病抑郁的疗效，强调了及时发现和协调处理的重要性。
Depressive disturbances are common in patients with Parkinson’s disease (PD) and influence many other clinical aspects of the disease. In addition to causing inherent emotional distress, depressive disorders negatively impact quality of life, motor and cognitive deficits, functional disability, and other psychiatric comorbidities in patients with PD. Knowledge of the pathophysiology of PD depression remains limited. However, clinical studies demonstrate the efficacy of medications and psychotherapies for PD depression, underscoring the importance of their timely detection and concerted management.