Diagnosis, classification, and management of soft tissue sarcomas.

Diagnosis, classification, and management of soft tissue sarcomas.
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软组织肉瘤的诊断、分类和治疗。

DOI:
10.1177/107327480501200102
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发表时间:
2005
期刊:
Cancer control : journal of the Moffitt Cancer Center
影响因子:
--
通讯作者:
F. Hornicek
F. Hornicek
中科院分区:
--
文献类型:
--
作者:
H. Mankin;F. Hornicek

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背景
BACKGROUND Soft tissue sarcomas are challenging to oncologists due to their unique character, the infrequency of their occurrence, and the difficulties in predicting outcomes. Advances in imaging, as well as improvements in surgical techniques and adjunctive treatment methods, have improved care for patients with these unusual disorders. METHODS The various types of soft tissue tumors are defined, and the statistics for the Orthopaedic Oncology Group in relation to them are reviewed and compared with literature references. RESULTS The overall survival rate for 1,220 tumors treated at our institute from June 1972 to June of 2001 was 72%, with a wide range. Patients with leiomyosarcomas, clear cell sarcomas, and malignant fibrous histiocytomas had a poorer survival rate, while those with fibrosarcomas, liposarcomas, and neurofibrosarcomas fared better. Outcome was affected by patient age, tumor anatomic site, tumor stage, and a history of recurrence. CONCLUSIONS Competent imaging, predictive immunological and genetic studies, improved surgery, and newer methods of adjunctive and neoadjunctive treatment should result in improvements in outcomes for patients with these tumors.
透明细胞肉瘤或软组织恶性黑色素瘤:微卫星不稳定性与临床相关性的分子分析。
DOI: 10.1016/s0165-4608(98)00004-1
发表时间: 1998
影响因子: --
作者:
Aue,G;Hedges,LK;Schwartz,HS;Bridge,JA;Neff,JR;Butler,MG
通讯作者: Butler,MG
DOI: 10.1200/jco.1996.14.5.1679
发表时间: 1996-05-01
影响因子: 45.3
作者:
Pisters, PWT;Leung, DHY;Brennan, MF
通讯作者: Brennan, MF
DOI: 10.1056/nejm199102143240702
发表时间: 1991-02-14
影响因子: 158.5
作者:
FLETCHER, JA;KOZAKEWICH, HP;CORSON, JM
通讯作者: CORSON, JM