Refractive Errors in a Rural Chinese Adult Population The Handan Eye Study
Refractive Errors in a Rural Chinese Adult Population The Handan Eye Study
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DOI：
10.1016/j.ophtha.2009.04.040
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发表时间：
2009-11-01
期刊：
影响因子：
13.7
通讯作者：
Friedman, David S.
中科院分区：
文献类型：
--
作者：
Liang, Yuan Bo;Wong, Tien Yin;Friedman, David S.
目的：描述中国农村成年人近视和其他屈光不正的患病率和危险因素。设计：基于人群的横断面研究。参与者：采用整群随机抽样方法，从中国邯郸选择7557名年龄≥ 30岁的中国人。方法：所有符合条件的受试者均被邀请接受全面的眼科检查，包括标准化屈光检查。近视、高度近视和远视分别定义为右眼等效球镜（SE）大于-0.5屈光度（D）、小于-5.0 D和0.5 D或以上。散光小于-0.5D柱镜。屈光参差定义为两眼之间的SE差异>1.0 D。主要结果测量：近视和其他屈光不正。结果：我们包括6491（85.9%的参与率）在这项研究中合格的科目。根据2000年中国人口普查调整后，近视患病率为26.7%（95%置信区间[CI]，25.6-27.8），远视患病率为15.9%（95% CI，15.0-16.8），散光患病率为24.5%（95% CI，23.5-25.5），屈光参差患病率为7.7%（95% CI，7.0-8.4）。高度近视的患病率为1.8%（95%CI，1.5-2.1）。使用多变量回归模型，目前吸烟（比值比[OR]，0.7，95% CI，0.5-0.9），阅读时间（OR，1.2; 95% CI，1.1-1.4），糖尿病（OR，8.4; 95%CI，2.2-32.5）和患有近视的家庭成员数量（OR，1.3; 95%CI，1.1-1.7，每个家庭成员）与年轻人（30-49岁）的近视相关。高中或高等教育（OR，1.8; 95% CI，1.1-3.1），糖尿病（OR，1.6; 95% CI，1.2-2.7），核混浊（OR，1.7; 95%CI，1.2-2.3），以及近视家庭成员人数（OR，1.5; 95%CI，1.2-1.9）是≥ 50岁人群的危险因素。结论：近视影响超过四分之一的农村≥ 30岁人群。近视在年轻人中更常见，与老年人相比，近视与不同的风险因素有关。财务披露：作者对本文中讨论的任何材料没有专有或商业利益。Ophthalmology 2009;116：2119-2127（C）2009，美国眼科学会。
Purpose: To describe the prevalence of and risk factors for myopia and other refractive errors in a rural, adult, Chinese population.Design: Population-based, cross-sectional study.Participants: A clustered, random sampling procedure was used to select 7557 Chinese people aged >= 30 years from Handan, China.Methods: All eligible subjects were invited to undergo a comprehensive eye examination, including standardized refraction. Myopia, high myopia, and hyperopia were defined as a spherical equivalent (SE) in the right eye of more than -0.5 diopter (D), less than -5.0 D, and 0.5 D or more, respectively. Astigmatism was less than -0.5 D of cylinder. Anisometropia was defined as a difference in SE of >1.0 D between the 2 eyes. Only phakic eyes were analyzed.Main Outcome Measures: Myopia and other refractive errors.Results: We included 6491 (85.9% participation rate) eligible subjects in this study. Adjusted to the 2000 China population census, the prevalence rate of myopia was 26.7% (95% confidence interval [CI], 25.6-27.8), hyperopia 15.9 % (95% CI, 15.0-16.8), astigmatism 24.5% (95% CI, 23.5-25.5), and anisometropia 7.7% (95% CI, 7.0-8.4). The prevalence of high myopia was 1.8% (95% CI, 1.5-2.1). Using a multivariate regression model, current smoking (odds ratio [OR], 0.7, 95% CI, 0.5-0.9), hours of reading (OR, 1.2; 95% CI, 1.1-1.4), diabetes (OR, 8.4; 95% CI, 2.2-32.5), and number of family members with myopia (OR, 1.3; 95% CI, 1.1-1.7, for each family member) were associated with myopia in younger persons (30-49 years). High school or higher education (OR, 1.8; 95% CI, 1.1-3.1), diabetes (OR, 1.6; 95% CI, 1.2-2.7), nuclear opacity (OR, 1.7; 95% CI, 1.2-2.3), and number of family members with myopia (OR, 1.5; 95% CI, 1.2-1.9) were risk factors in persons >= 50 years of age.Conclusions: Myopia affects more than one quarter of rural Chinese persons >= 30 years of age. Myopia is more common in younger people and is associated with different risk factors than in older people.Financial Disclosure(s): The authors have no proprietary or commercial interest in any materials discussed in this article. Ophthalmology 2009;116:2119-2127 (C) 2009 by the American Academy of Ophthalmology.