Clubgoers and their trendy cocktails: Implications of mixing caffeine into alcohol on information processing and subjective reports of intoxication
Clubgoers and their trendy cocktails: Implications of mixing caffeine into alcohol on information processing and subjective reports of intoxication
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DOI：
10.1037/1064-1297.14.4.450
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发表时间：
2006-11-01
影响因子：
2.3
通讯作者：
Fillmore, Mark T.
中科院分区：
文献类型：
--
作者：
Marczinski, Cecile A.;Fillmore, Mark T.
最近，大学生的酒精饮料偏好发生了有趣的变化，消费趋势倾向于各种形式的含咖啡因的酒精（例如，红牛和伏特加或含咖啡因的啤酒，如安海斯-布希的B到E）。尽管这些饮料的受欢迎程度急剧上升，但很少有研究考察酒精和咖啡因的综合作用，这对于充分告知公众这些饮料的风险或缺乏这些饮料是有问题的。本研究的目的是直接调查酒精和咖啡因，单独和组合，对社交饮酒者的认知表现和主观中毒的有效措施的急性影响。参与者（N = 12）进行了一项心理不应期任务，测量双任务干扰作为延长的反应时间，以完成2个任务中的第2个在关闭的时间序列。在2个活性剂量和1个安慰剂剂量的咖啡因（0.0 mg/kg、2.0 mg/kg和4.0 mg/kg）与1个活性剂量和1个安慰剂剂量的酒精（0.0 g/kg和0.65 g/kg）组合下测试性能。正如预期的那样，酒精通过增加双任务干扰和增加错误来损害任务表现。咖啡因的共同管理抵消了酒精对干扰的影响，但对酒精增加错误的程度没有影响。中毒的主观测量表明，与单独使用酒精相比，咖啡因与酒精同时使用降低了参与者对酒精中毒的感知。结果突出了酒精和咖啡因之间药物相互作用的复杂性。
Alcoholic drink preferences in college students have made an interesting shift recently, with trends in consumption leaning toward caffeinated alcohol in various forms (e.g., Red Bull and vodka or caffeinated beers such as Anheuser-Busch's B-to-the-E). Despite the dramatic rise in popularity of these beverages, little research has examined the combined effects of alcohol and caffeine, which is problematic for adequately informing the public about the risk or lack thereof of these drinks. The purpose of this study was to directly investigate the acute effects of alcohol and caffeine, alone and in combination, on well-validated measures of cognitive performance and subjective intoxication in social drinkers. Participants (N = 12) performed a psychological refractory period task that measured dual-task interference as the prolonged reaction time to complete the 2nd of 2 tasks performed in close temporal sequence. Performance was tested under 2 active doses and 1 placebo dose of caffeine (0.0 mg/kg, 2.0 mg/kg, and 4.0 mg/kg) in combination with I active dose and 1 placebo dose of alcohol (0.0 g/kg and 0.65 g/kg). As expected, alcohol impaired task performance by increasing dual-task interference and increasing errors. The coadministration of caffeine counteracted the effects of alcohol on interference but had no effect on the degree to which alcohol increased errors. Subjective measures of intoxication showed that coadministration of caffeine with alcohol reduced participants' perceptions of alcohol intoxication compared with administration of alcohol alone. The results highlight the complexity of drug interactions between alcohol and caffeine.