Urinary catecholamines and salivary cortisol on workdays and days off in relation to job strain among female health care providers
Urinary catecholamines and salivary cortisol on workdays and days off in relation to job strain among female health care providers
复制标题
DOI：
10.5271/sjweh.770
复制
发表时间：
2004-04-01
影响因子：
6.3
通讯作者：
Kishi, R
中科院分区：
文献类型：
--
作者：
Fujiwara, K;Tsukishima, E;Kishi, R
目的探讨心理社会工作紧张对神经内分泌应激激素分泌的影响方法16名日本女性医护人员填写Karasek的工作内容调查表，（即尿中的儿茶酚胺和唾液皮质醇）在休息日和两个工作日（一个白班和一个夜班）测量。控制后的年龄和工作经验作为协变量，重复测量的方差analysis.Results去甲肾上腺素排泄显着大于随着时间的推移，在高应变组比低应变组，高需求组是显着大于随着时间的推移，比低需求组。两组间肾上腺素排泄无显著差异。高监督支持组的肾上腺素排泄量显著高于低监督支持组。唾液皮质醇的浓度在一个白班显着降低，但轻微，在高应变组比在低应变group.Conclusions心理社会工作压力与更大的去甲肾上腺素排泄随着时间的推移。这一发现表明交感神经活动正在放松。高紧张组的皮质醇水平较低，可能反映了工作紧张引起的昼夜节律紊乱。监督的关系可能有一个特殊的影响，因为参与者有更多的行政接触，主管比支持在工地，因此，监督的支持可能会增加肾上腺素的分泌。
Objectives This study examined the effects of psychosocial job strain on the excretion of neuroendocrine stress hormones (adrenaline, noradrenaline, and cortisol) on workdays and days off.Methods Japanese female healthcare providers (N=16) filled out Karasek's job content questionnaire and had their neuroendocrine excretions (ie, urinary catecholamines and salivary cortisol) measured on a day off and on two workdays (one day shift and one night shift). After control for age and job experience as covariates, a repeated-measures analysis of variance was carried out.Results Noradrenaline excretion was significantly greater over time in the high-strain group than in the low-strain group, and that of the high-demand group was significantly greater over time than that of the low-demand group. Adrenaline excretion did not significantly differ between the groups. The group with high supervisory support had significantly higher adrenaline excretion than the group with low supervisory support. The concentration of salivary cortisol on a dayshift was significantly lower, but marginally, in the high-strain group than in the low-strain group.Conclusions Psychosocial job strain is associated with greater noradrenaline excretion over time. This finding suggests unwinding sympathetic nervous activity. The low cortisol levels of the high-strain group may indicate circadian rhythm disturbance induced by job strain. Supervisory relationships may have a particular influence for the studied occupation because the participants had more administrative contact with supervisors than support at the worksite; therefore, supervisory support may increase adrenaline excretion.