Obesity and fat distribution in relation to hot flashes in Dutch women from the DOM-project
Obesity and fat distribution in relation to hot flashes in Dutch women from the DOM-project
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DOI：
10.1016/0378-5122(95)00990-6
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发表时间：
1996-04-01
期刊：
影响因子：
4.9
通讯作者：
vanNoord, PAH
中科院分区：
文献类型：
--
作者：
denTonkelaar, I;Seidell, JC;vanNoord, PAH
作者在一项基于人群的研究中研究了肥胖和脂肪分布与潮热发生的关系，该研究包括 2904 名 40-44 岁女性和 569 名 54-69 岁女性进行乳房 X 光检查（DOM 项目）。年龄在 40-44 岁之间，处于 Quetelet 指数和腰臀比较高三分位数的女性报告潮热的频率明显高于相应较低三分位数的女性。这些关联彼此独立且与年龄无关。调整年龄、腰臀比和绝经状态后，比较 Quetelet 指数上三分位数与下三分位数的比值比为 1.70（95% 置信区间，1.30-2.21）。调整年龄、Quetelet 指数和绝经状态后，腰臀比上三分位数与下三分位数的比值比为 1.37（95% CI，1.05-1.78）。在 54-69 岁的女性中，没有观察到 Quetelet 指数与潮热主诉之间存在显着关联。腰臀比上三分位的女性比下三分位的女性更常报告潮热，但这一结果并不显着（OR 1.38；95% CI，0.87-2.22）。
The authors studied obesity and fat distribution in relation to the occurrence of hot flashes in a population-based study comprising 2904 women aged 40-44 and 569 women aged 54-69 presenting for mammographic screening (the DOM-project). Women aged 40-44 in the upper tertiles of Quetelet's index and waist/hip ratio reported hot flashes significantly more often than women in the respective lower tertiles. These associations were independent of each other and independent of age. After adjustment for age, waist/hip ratio and menopausal status, the odds ratio comparing the upper tertile of Quetelet's index to the lower tertile was 1.70 (95% confidence interval, 1.30-2.21). After adjustment for age, Quetelet's index and menopausal status, the odds ratio comparing the upper tertile of waist/hip ratio to the lower tertile was 1.37 (95% CI, 1.05-1.78). In women aged 54-69 no significant associations between Quetelet's index and complaints of hot flashes were observed. Women in the upper tertile of waist/hip ratio reported hot flashes more often than women in the lower tertile, but this result was not significant (OR 1.38; 95% CI, 0.87-2.22).