Inhibitory effect on S. mutans by fluoride-treated conventional and resin-reinforced glass ionomer cements.
Inhibitory effect on S. mutans by fluoride-treated conventional and resin-reinforced glass ionomer cements.
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氟化物处理的常规和树脂增强玻璃离子水门汀对变形链球菌的抑制作用。
DOI：
10.1111/j.1600-0722.1995.tb00022.x
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发表时间：
1995
影响因子：
1.9
通讯作者：
A. Nuutinen
中科院分区：
文献类型：
--
作者：
L. Seppä;A. Korhonen;A. Nuutinen
本研究的目的是研究氟凝胶处理对氟释放的影响，以及不同玻璃离子水合物对变形链球菌产酸的抑制作用。四种玻璃离聚体材料的测试板被安装在试管的底部。将一层变形链球菌细胞离心到实验板上，在1.7%蔗糖溶液中孵育4 h。用新鲜、陈化（29 d）、陈化和f处理（1.25% f凝胶）、陈化、f处理和陈化样品孵育（每组n = 15）。每次孵育后，测定液相pH和F的含量。新混合的玻璃离聚体样品释放出大量的氟化物，并且明显抑制了流体相的pH下降。对于老化样品，氟释放量明显下降，对变形链球菌产酸无抑制作用。应用氟凝胶后，氟的释放和抑制效果均显著高于初始水平。综上所述，所有的玻璃离子水合物都能够吸收氟化物并随后释放出来，从而恢复了它们的抗菌效果。氟化物的释放模式和抗菌作用对于传统的和树脂增强的玻璃离子聚合物水泥几乎是相同的。
The aim of the present study was to study the effect of fluoride gel treatment on fluoride release and inhibition of acid production of Streptococcus mutans by different glass ionomer cements. Test slabs of four glass ionomer materials were fitted into the bottom of a test tube. A layer of S. mutans cells was centrifuged onto the test slabs, and the specimens were incubated for 4 h in 1.7% sucrose solution. Incubations were made using fresh, aged (29 d), aged and F-treated (1.25% F-gel), and aged, F-treated and aged samples (n = 15 per group). After each incubation, pH and F contents of the fluid phase were determined. The freshly mixed glass ionomer samples released large amounts of fluoride, and the pH fall in the fluid phase was significantly inhibited. For aged samples, the fluoride release decreased strongly and no inhibitory effect on acid production by S. mutans was seen. After application of fluoride gel, fluoride release and inhibitory effect were significantly higher than initially for all glass ionomer cements. In conclusion, all glass ionomer cements were able to take up fluoride and subsequently release it, which resulted in reestablishment of their antibacterial effect. The patterns of fluoride release and antibacterial action were virtually the same for conventional and resin-reinforced glass ionomer cements.