Excessive Weight Gain among Obese Women and Pregnancy Outcomes
Excessive Weight Gain among Obese Women and Pregnancy Outcomes
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DOI：
10.1055/s-0029-1243304
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发表时间：
2010-04-01
影响因子：
2
通讯作者：
Gonzalez-Quintero, Victor Hugo
中科院分区：
文献类型：
--
作者：
Flick, Amy A.;Brookfield, Kathleen F.;Gonzalez-Quintero, Victor Hugo
我们评估了妊娠期体重过度增加的肥胖妇女的妊娠结局。对所有肥胖妇女进行了回顾性研究。结局包括先兆子痫（PEC）、妊娠期糖尿病、剖宫产（CD）、早产、低出生体重、极低出生体重、巨大儿、5分钟Apgar评分≥ 40 kg/m2的发生率。从母亲的医疗图表中提取了GEORGE体重变化，并将其分为四类：体重减轻，体重增加高达14.9磅，体重增加15至24.9磅，体重增加超过25磅。共有20，823名肥胖女性有资格参加这项研究。单因素分析显示，与I类肥胖妇女相比，II类和III类肥胖妇女的先兆子痫、妊娠期糖尿病、剖宫产、早产、低出生体重、巨大儿和新生儿重症监护室入院率较高。当使用不同的体重增加模式作为逻辑回归模型时，PEC和CD的比率增加。肥胖女性体重过度增加与不良结局相关，随着BMI增加，风险更高。
We evaluated pregnancy outcomes in obese women with excessive weight gain during pregnancy. A retrospective study was performed on all obese women. Outcomes included rates of preeclampsia (PEC), gestational diabetes, cesarean delivery (CD), preterm delivery, low birth weight, very low birth weight, macrosomia, 5-minute Apgar score of = 40 kg/m(2)). Gestational weight change was abstracted from the mother's medical chart and was divided into four categories: weight loss, weight gain of up to 14.9 pounds, weight gain of 15 to 24.9 pounds, and weight gain of more than 25 pounds. A total 20,823 obese women were eligible for the study. Univariate analysis revealed higher rates of preeclampsia, gestational diabetes, Cesarean deliveries, preterm deliveries, low birth weight, macrosomia, and NICU admission in class II and class III obese women when compared with class I women. When different patterns of weight gain were used as in the logistic regression model, rates of PEC and CD were increased. Excessive weight gain among obese women is associated with adverse outcomes with a higher risk as BMI increases.