RED-CELL EXTENSIONAL RECOVERY AND THE DETERMINATION OF MEMBRANE VISCOSITY

RED-CELL EXTENSIONAL RECOVERY AND THE DETERMINATION OF MEMBRANE VISCOSITY
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DOI:
10.1016/s0006-3495(79)85238-8
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发表时间:
1979-01-01
影响因子:
3.4
通讯作者:
EVANS, EA
EVANS, EA
中科院分区:
生物学3区
文献类型:
--
作者:
HOCHMUTH, RM;WORTHY, PR;EVANS, EA

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Evans和Hochmuth在1976年提出的膜粘弹性理论被用来分析延长细胞的时间依赖性恢复。在释放前,细长细胞处于静态平衡状态,外力由膜弹性力产生平衡。释放后,细胞恢复其初始形状,具有粘弹性实体模型的时间依赖指数行为特征。该模型在0.1 ~ 0.13 s的时间常数范围内很好地描述了随时间变化的恢复过程。时间常数为膜表面粘度的比值。:膜表面弹性;剪切模量的测量。mu。当0.006达因/厘米时,红细胞膜作为粘弹性固体材料的表面粘度值为。eta。= .mu。Tc =(6-8)。10-4平衡。厘米。
A theory of membrane viscoelasticity developed by Evans and Hochmuth in 1976 was used to analyze the time-dependent recovery of an elongated cell. Before release, the elongated cell was in static equilibrium where external forces are balanced by membrane elastic force resultants. Upon release, the cell recovered its initial shape with a time-dependent exponential behavior characteristic of the viscoelastic solid model. The model described the time-dependent recovery process very well for a time constant in the range of 0.1-0.13 s. The time constant is the ratio membrane surface viscosity .eta.:membrane surface elasticity .mu.. Measurements for the shear modulus .mu. of 0.006 dyne/cm gave a value for the surface viscosity of red cell membrane as a viscoelastic solid material of .eta. = .mu.tc = (6-8) .times. 10-4 poise .cntdot. cm.