An exact test for detecting inconsistency in readers interpretation over time in screening mammograms.
An exact test for detecting inconsistency in readers interpretation over time in screening mammograms.
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一项精确测试，用于检测筛查乳房 X 光检查中读者解读随时间的不一致情况。
DOI：
10.1002/bimj.200610314
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发表时间：
2007
期刊：
影响因子：
--
通讯作者：
Beam,Craig
中科院分区：
文献类型：
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作者：
Lee,Ji-Hyun;Eschrich,Steven;Beam,Craig
放射科医生对筛查性乳腺X线片的解释是通过准确性指标来衡量的，如灵敏度和特异性。放射科医生对筛查性乳房X线照片的解释在时间上是恒定的这一假设可以通过测量过度分散来检验。然而，小样本量是渐近方法的准确性的问题。在这篇文章中，我们提出了一个确切的条件分布，用于测试的二项假设的过度分散的准确性指标。可以从开发的分布中定义精确的值。我们还描述了一个算法来计算这个确切的测试。将所提出的方法应用于来自在美国放射科医师群体中阅读筛查乳房X线照片的研究的数据（Beam等人，2003年）。精确的方法进行了比较分析与目前可用的方法的基础上大样本近似。（© 2007 WILEY‐VCH Verlag GmbH & Co. KGaA，魏因海姆）
Radiologists' interpretation on screening mammograms is measured by accuracy indices such as sensitivity and specificity. The hypothesis that radiologists' interpretation on screening mammograms is constant across time can be tested by measuring overdispersion. However, small sample sizes are problematic for the accuracy of asymptotic approaches. In this article, we propose an exact conditional distribution for testing overdispersion of the binomial assumption that is assumed for the accuracy indices. An exactp‐value can be defined from the developed distribution. We also describe an algorithm for computing this exact test. This proposed method is applied to data from a study in reading screening mammograms in a population of US radiologists (Beam et al., 2003). The exact method is compared analytically with a currently available method based on large sample approximations. (© 2007 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)