Intralesional injection of platelet-rich plasma followed by controlled exercise for treatment of midbody suspensory ligament desmitis in Standardbred racehorses
Intralesional injection of platelet-rich plasma followed by controlled exercise for treatment of midbody suspensory ligament desmitis in Standardbred racehorses
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DOI：
10.2460/javma.232.10.1515
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发表时间：
2008-05-15
影响因子：
1.9
通讯作者：
Bertone, Alicia L.
中科院分区：
文献类型：
--
作者：
Waselau, Martin;Sutter, W. Wesley;Bertone, Alicia L.
目的-通过超声引导下病灶内注射单剂量富血小板血浆（PRP），然后逐渐增加运动量，确定患有中度至重度中段悬韧带韧带炎（MSD）的Standardbred赛马的结果。设计-非随机临床试验。动物- 9匹Standardbred赛马。程序-注射PRP后，允许对照，逐步恢复锻炼。审查了马匹受伤前一年和重返比赛后连续3年的比赛记录。为了比较的目的，9 Standardbred赛马没有历史的MSD赛车在同一时间的比赛记录也reviewed.Results -所有9匹马与MSD治疗后返回比赛，返回比赛的中位时间为32周。所有9匹马在返回比赛后的第一年和第二年至少参加了一次比赛，但只有5匹马在第三年参加了比赛。当比较病例马和对照马的起跑数、总收入和每次起跑的收入时，唯一显著的差异是病例马返回比赛后第三年的起跑数和病例马返回比赛后第一年的每次起跑的收入，病例马的值显著低于对照马。结论和临床相关性-结果表明，通过病灶内注射单剂量PRP治疗中度至重度MSD的马，然后进行逐渐增加运动的计划，恢复比赛的预后良好。
Objective - To determine outcome of Standardbred racehorses with moderate to severe midbody suspensory ligament desmitis (MSD) treated by means of ultrasound-guided intralesional injection of a single dose of platelet-rich plasma (PRP) followed by a program of gradually increased exercise.Design - Nonrandomized clinical trial.Animals - 9 Standardbred racehorses.Procedures - Following injection of PRP horses were allowed a controlled, gradual return to exercise. Race records for the year prior to injury and for 3 consecutive years after horses returned to racing were reviewed. For comparison purposes, race records of 9 Standardbred racehorses with no history of MSD racing at the same time were also reviewed.Results - All 9 horses with MSD returned to racing after treatment; median time to return to racing was 32 weeks. All 9 horses raced at least once during the first and second years after returning to racing, but only 5 raced during the third year. When number of starts, total earnings, and earnings per start were compared between case and comparison horses, the only significant differences were number of starts during the third year after case horses returned to racing and earnings per start during the first year after case horses returned to racing, with values being significantly lower for case horses than for comparison horses.Conclusions and Clinical Relevance - Results suggested that horses with moderate to severe MSD treated by means of intralesional injection of a single dose of PRP followed by a program of gradually increased exercise had an excellent prognosis for returning to racing.