Adsorption semiconductor sensor for diabetic ketoacidosis diagnosis
Adsorption semiconductor sensor for diabetic ketoacidosis diagnosis
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DOI：
10.1016/s0925-4005(97)80107-4
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发表时间：
1996-10-01
影响因子：
8.4
通讯作者：
Martynenko, F
中科院分区：
文献类型：
--
作者：
Makisimovich, N;Vorotyntsev, V;Martynenko, F
揭示了糖尿病患者血液中丙酮浓度与空气中丙酮浓度的相关性。这一相关性可作为有创呼气分析患者血液中丙酮测定的基本相关性。干扰丙酮测定的因素有：(i)分析前吸烟和（ii）分析时患者血液中存在酒精。在研制的传感器基础上，根据人体呼出动力学的特点，设计了呼气中丙酮含量测定酮症酸中毒诊断仪器。所设计的丙酮测定装置是一种快速测定装置。它更简单，不涉及特殊的载气，比GLC或光度法分析更便宜。
The correlation of acetone concentration in blood with that in the air expired by patients suffered from diabetes mellitus was revealed. This correlation may become the basic one for invasive acetone determination in patient's blood via analysis of the air expired. The factors which interfere with acetone determination are: (i) smoking just before the analysis and (ii) the alcohol presence in patients' blood at the moment of analysis. Based on the sensor developed, the apparatus was designed for ketoacidosis diagnosis by means of acetone determination in expired air accounting for the peculiarities of human breath-out dynamics. Acetone determination by means of the apparatus designed is an express one. It is much more simple, does not involve special carrier gas and is less expensive than GLC or photometry analysis.